PDF(Pubmed)
Abstract：
Coronavirus disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is recognized for its heterogeneous clinical presentation, complex pathophysiology, and broad spectrum of manifestations. Obstetric patients have been a subject of considerable interest due to their potential vulnerability to more severe infection and adverse pregnancy outcomes, exemplified by this report of a 43-year-old pregnant female with severe COVID-19 infection and respiratory complications. This case report aims to contribute to the existing scientific knowledge by presenting a detailed clinical profile of a patient with COVID-19 who achieved pregnancy through in vitro fertilization (IVF) and discussing the management and outcomes of the infection. The neonate\'s negative COVID-19 tests suggest no intrauterine transmission; prompt medical interventions, including mechanical ventilation and targeted antibiotic therapy, were implemented to stabilize her condition. Close collaboration among the multidisciplinary team and careful monitoring of vital functions and laboratory parameters were crucial in managing the patient\'s complex condition. Thus, this case highlights the importance of a comprehensive and multidisciplinary approach in managing severe COVID-19 cases in pregnancy, emphasizing the need for prompt recognition of complications and timely intervention.
摘要：
2019年冠状病毒病（COVID-19），由新型严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引起的疾病，因其异质性临床表现而得到认可，复杂的病理生理学，和广泛的表现。产科患者一直是一个相当感兴趣的对象，因为他们可能容易受到更严重的感染和不良的妊娠结局，以一名43岁孕妇患有严重COVID-19感染和呼吸道并发症的报告为例。本病例报告旨在通过提供一名通过体外受精(IVF)怀孕的COVID-19患者的详细临床资料，并讨论感染的管理和结果，为现有的科学知识做出贡献。新生儿COVID-19检测阴性提示无宫内传播；及时医疗干预，包括机械通气和靶向抗生素治疗，是为了稳定她的病情.多学科团队之间的密切合作以及对重要功能和实验室参数的仔细监测对于管理患者的复杂状况至关重要。因此，该病例强调了综合和多学科方法在管理妊娠严重COVID-19病例中的重要性，强调需要及时识别并发症和及时干预。
