光学相干断层扫描引导的布里渊显微镜在 Mthfd1l 鼠突变体的前神经管闭合过程中突出区域组织硬度差异。
关键词: Biomechanics Brillouin microscopy Mouse Neural tube closure Neural tube defects
Mesh : Animals Female Mice Biomechanical Phenomena Embryo, Mammalian / metabolism Formate-Tetrahydrofolate Ligase / genetics metabolism Formates / metabolism Methylenetetrahydrofolate Dehydrogenase (NADP) / genetics metabolism Mice, Knockout Microscopy, Confocal Mutation / genetics Neural Tube / metabolism Neural Tube Defects / genetics metabolism pathology Neurulation / genetics Tomography, Optical Coherence / methods
来 源:
DOI:10.1242/dev.202475
PDF(Pubmed)