METHODS: Women aged 40-55 years presenting with heavy menstrual bleeding at the gynaecology outpatient department at Sree Balaji Medical College and Hospital, Chennai, India, were included in the study. Patients on anti-platelet and anti-coagulation therapy and patients already on hormonal treatment for heavy menstrual bleeding were excluded from the study. The demographic factors, symptom profiles, ultrasound findings, and histopathological reports were tabulated and analysed.
RESULTS: Of the 147 women included in the study, 75 (51%) were aged 45-50 years and 107 (73%) had two or more pregnancies. Fibroid was the common non-endometrial cause of heavy menstrual bleeding in 52 (35%) cases. The proliferative pattern was the most common non-pathological histology identified in 46 (31%) cases. Endometrial hyperplasia without atypia was the most common pathological histology observed in the study population. Endometrial thickness of more than 8 mm was strongly associated with premalignant or malignant endometrial lesions.
CONCLUSIONS: Our study has attempted to identify the correlation between ultrasound evaluation of perimenopausal women with heavy menstrual bleeding and endometrial pathology. Ultrasound, being cost-effective and widely available, is proven to be a tool for first-line investigation of perimenopausal women with heavy menstrual bleeding that guides further evaluation and management.
方法:在SreeBalaji医学院和医院妇科门诊部出现大量月经出血的40-55岁女性,钦奈,印度,包括在研究中。接受抗血小板和抗凝治疗的患者以及已经接受激素治疗的月经大量出血的患者被排除在研究之外。人口因素,症状简介,超声检查结果,和组织病理学报告进行列表和分析。
结果:在纳入研究的147名女性中,75(51%)年龄在45-50岁之间,107(73%)有两次或更多次怀孕。在52例(35%)中,子宫肌瘤是月经大量出血的常见非子宫内膜原因。在46例(31%)病例中,增殖模式是最常见的非病理性组织学。无异型性的子宫内膜增生是在研究人群中观察到的最常见的病理组织学。子宫内膜厚度超过8mm与子宫内膜癌前病变或恶性病变密切相关。
结论:我们的研究试图确定围绝经期重度月经出血妇女的超声评估与子宫内膜病理之间的相关性。超声波,具有成本效益和广泛可用,已被证明是对围绝经期大量月经出血妇女进行一线调查的工具,可指导进一步的评估和管理。