关键词: Community-adquired pneumonia Legionella pneumophila Legionnaires' disease Septic shock

Mesh : Humans Community-Acquired Infections / microbiology drug therapy diagnosis Legionella pneumophila / isolation & purification genetics Shock, Septic / microbiology Legionnaires' Disease / diagnosis microbiology Fatal Outcome Male Aged Serogroup Middle Aged

来  源:   DOI:10.1016/j.jiph.2024.04.019

Abstract:
Legionellers\' desease accounts for 1-8 % of cases of severe community-acquired pneumonia (CAP). Legionella spp. Is the causative organism that can result in respiratory failure, multi-organ dysfunction, sepsis, and death. Therefore, rapid diagnosis and efficient treatment are crucial. We report the clinical and microbiology study of a patient with community-acquired pneumonia caused by Legionella pneumophila, with fatal outcome. After death, the strain causing the infection was identified as Legionella pneumophila serogroup 1, Olda OLDA phenotype and sequence-type 1. This is the first reported case of septic shock and death associated with an isolate of these characteristics.
摘要:
退伍军人症占严重社区获得性肺炎(CAP)病例的1-8%。军团菌属。是导致呼吸衰竭的病原体,多器官功能障碍,脓毒症,和死亡。因此,快速诊断和有效治疗至关重要。我们报告了由嗜肺军团菌引起的社区获得性肺炎患者的临床和微生物学研究,致命的结果。死后,导致感染的菌株被鉴定为嗜肺军团菌血清群1,OldaOLDA表型和序列型1。这是第一例报道的与这些特征的分离有关的脓毒性休克和死亡病例。
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