关键词: Androgens Estrogens Gonadotropins Hypogonadotropic hypogonadism Klinefelter syndrome Minipuberty Turner syndrome

Mesh : Humans Turner Syndrome / drug therapy complications Hypogonadism / drug therapy etiology Klinefelter Syndrome / complications drug therapy Infant Male Child, Preschool Female Hormone Replacement Therapy / methods Child Gonadotropins / therapeutic use

来  源:   DOI:10.1016/j.ecl.2024.02.003

Abstract:
Managing patients unable to produce sex steroids using gonadotropins to mimic minipuberty in hypogonadotropic hypogonadism, or sex steroids in patients with Klinefelter or Turner syndrome, is promising. There is a need to pursue research in this area, with large prospective cohorts and long-term data before these treatments can be routinely considered.
摘要:
使用促性腺激素来管理无法产生性类固醇的患者,以模拟低促性腺激素性腺功能减退的小青春期,或者Klinefelter或Turner综合征患者的性类固醇,很有希望。有必要在这方面进行研究,在这些治疗之前,可以常规考虑大量前瞻性队列和长期数据。
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