Abstract：
A thorough history and physical examination including Tanner staging and growth assessments can guide differential diagnosis and aid in the evaluation of precocious puberty. Basal luteinizing hormone levels measured using a highly sensitive assay can be helpful in diagnosing central precocious puberty (CPP). Brain MRI is indicated with males diagnosed with CPP and females under the age of 6 with CPP. As more information becomes available regarding the genetic etiologies of CPP, genetic testing may preclude the need for imaging studies and other hormonal testing, especially in familial cases.
摘要：
全面的病史和体格检查，包括坦纳分期和生长评估，可以指导鉴别诊断，并有助于评估性早熟。使用高度敏感的测定法测量的基础黄体生成素水平可有助于诊断中枢性早熟（CPP）。诊断为CPP的男性和患有CPP的6岁以下女性的脑部MRI显示。随着更多关于CPP遗传病因的信息变得可用，基因检测可能排除了成像研究和其他激素检测的需要，尤其是家族性病例。
