%0 Journal Article %T Diagnosis of Central Precocious Puberty. %A Bangalore Krishna K %A Silverman LA %J Endocrinol Metab Clin North Am %V 53 %N 2 %D 2024 Jun %M 38677865 %F 4.748 %R 10.1016/j.ecl.2024.02.002 %X A thorough history and physical examination including Tanner staging and growth assessments can guide differential diagnosis and aid in the evaluation of precocious puberty. Basal luteinizing hormone levels measured using a highly sensitive assay can be helpful in diagnosing central precocious puberty (CPP). Brain MRI is indicated with males diagnosed with CPP and females under the age of 6 with CPP. As more information becomes available regarding the genetic etiologies of CPP, genetic testing may preclude the need for imaging studies and other hormonal testing, especially in familial cases.