Abstract：
Anal intraepithelial neoplasia (AIN) are precancerous lesions and are sequela of human papilloma virus (HPV) infection. AIN is classified as low-grade squamous intraepithelial lesion or high-grade squamous intraepithelial lesion. Screening with anal cytology and anoscopy should be considered for high-risk populations. Diagnosis is made through high resolution anaoscopy and biopsy. Options for treatment include ablation and several topical therapies; however, recurrence rates are high for all treatment options, and an ongoing surveillance is necessary to prevent progression to anal squamous cell carcinoma. HPV vaccination is recommended to prevent disease.
摘要：
肛门上皮内瘤变（AIN）是癌前病变，是人乳头瘤病毒（HPV）感染的后遗症。AIN分为低度鳞状上皮内病变或高度鳞状上皮内病变。对于高危人群，应考虑使用肛门细胞学和肛门镜检查进行筛查。通过高分辨率镜检查和活检进行诊断。治疗方案包括消融和几种局部治疗；然而，所有治疗方案的复发率都很高，持续监测是必要的，以防止发展为肛门鳞状细胞癌。建议接种HPV疫苗以预防疾病。
