PDF(Pubmed)
Abstract：
Digitized assessments have a considerable potential to guide clinicial decision making and monitor progress and disease trajectories. The Timed Up and Go test (TUG) has been long established for assessment in geriatric medicine and instrumented versions (iTUG) have been developed and validated. This scoping review includes studies that applied the iTUG and aims to identify use cases to show where and how iTUG assessment could guide interventions and clinical management. The literature search was limited to peer-reviewed studies that performed pre- and post-intervention measurements with a 3-meter TUG instrumented with body-worn technology in samples of at least 20 subjects aged 60+ years. Of 3018 identified articles 20 were included. Four clinical use cases were identified: stratification for subsequent therapy, monitoring of disease or treatment-associated changes and evaluation of interventions in patients with idiopathic normal pressure hydrocephalus (1), and patients with Parkinson\'s disease (2); monitoring after joint replacement surgery (3), and evaluation after different exercise and rehabilitation interventions (4). The included studies show diversity in terms of iTUG technology and procedures. The identified use cases highlight clinical relevance and high potential for the clinical application of the iTUG. A consensual approach as well as comprehensive reporting would help to further exploit the potential of the iTUG to support clinical management. Future studies should investigate the benefits of segmental iTUG analysis, responsiveness and participants\' perspectives on clinically meaningful changes in iTUG.
摘要：
数字化评估在指导临床决策和监测进展和疾病轨迹方面具有相当大的潜力。长期以来，已建立了TimedUpandGo测试（TUG），用于评估老年医学，并开发和验证了仪器版本（iTUG）。本范围审查包括应用iTUG的研究，旨在确定用例，以显示iTUG评估在何处以及如何指导干预措施和临床管理。文献检索仅限于同行评审的研究，这些研究在至少20名60岁以上的受试者的样本中使用3米长的TUG进行了干预前后的测量。在3018条确定的文章中，包括20条。确定了四个临床用例：后续治疗的分层，监测特发性正常压力脑积水患者的疾病或治疗相关变化并评估干预措施（1），和帕金森病患者（2）；关节置换手术后的监测（3），并在不同的运动和康复干预后进行评估（4）。纳入的研究显示了iTUG技术和程序方面的多样性。确定的用例突出了临床相关性和iTUG临床应用的高潜力。协商一致的方法以及全面的报告将有助于进一步开发iTUG支持临床管理的潜力。未来的研究应该调查分段iTUG分析的好处，反应性和参与者对iTUG临床意义变化的看法。
