PDF(Pubmed)
Abstract：
Acanthamoeba keratitis (AK) is a rare but potentially sight-threatening corneal infection caused by the Acanthamoeba parasite. This microorganism is found ubiquitously in the environment, often in freshwater, soil, and other sources of moisture. Despite its low incidence, AK presents significant challenges due to delayed diagnosis and the complex nature of therapeutic management. Early recognition is crucial to prevent severe ocular complications, including corneal ulceration and vision loss. Diagnostic modalities and treatment strategies may vary greatly depending on the clinical manifestation and the available tools. With the growing reported cases of Acanthamoeba keratitis, it is essential for the ophthalmic community to thoroughly understand this condition for its effective management and improved outcomes. This review provides a comprehensive overview of AK, encompassing its epidemiology, risk factors, pathophysiology, clinical manifestations, diagnosis, and treatment.
摘要：
棘阿米巴角膜炎（AK）是由棘阿米巴寄生虫引起的一种罕见但可能威胁视力的角膜感染。这种微生物在环境中无处不在，通常在淡水中，土壤,和其他水分来源。尽管发病率低,由于延迟诊断和治疗管理的复杂性，AK提出了重大挑战。早期识别对于预防严重的眼部并发症至关重要，包括角膜溃疡和视力丧失。诊断方式和治疗策略可能会有很大差异，具体取决于临床表现和可用工具。随着越来越多的棘阿米巴角膜炎病例的报道，对于眼科界来说，彻底了解这种情况对于有效管理和改善结果至关重要。这篇综述全面概述了AK，包括它的流行病学，危险因素，病理生理学,临床表现，诊断,和治疗。
