PDF(Pubmed)
Abstract：
Background and Objectives: Patients at high altitudes with COVID-19 may experience a decrease in their partial oxygen saturation (PO2S) levels. The objective was to assess the association between PO2S and intensive care unit (ICU) stay in patients at high altitudes with COVID-19. Materials and Methods: Clinical records of 69 COVID-19 patients (36% women) admitted to the ICU were analyzed. Median values were considered for intra-group categories (\"≤11 days\" and \">11 days\" in the ICU) and for PO2S height categories (\"<90%\" and \"≥90%\"). Logistic regression and linear regression models adjusted for confounding variables were used. Results: Patients with >11 days in the ICU had 84% lower odds of having a PO2S ≥ 90% (OR: 0.16 [CI: 0.02, 0.69], p = 0.005) compared to those with ≤11 days in the ICU. An increase in PO2S by 1% reduced ICU stay by 0.22 days (β: -0.22 [CI: -0.33, -0.11], p < 0.001), potentially leading to a reduction of up to 1.44 days. Conclusions: PO2S is a crucial factor in estimating ICU stays for COVID-19 patients at high altitudes and serves as an accessible and cost-effective measure. It should be used in infected patients to complement the prognosis of post-pandemic ICU stay.
摘要：
背景和目的：高海拔地区COVID-19患者的部分氧饱和度（PO2S）水平可能会降低。目的是评估高海拔地区COVID-19患者PO2S与重症监护病房(ICU)住院时间之间的关系。材料与方法：对69例COVID-19患者（36％为女性）入住ICU的临床资料进行分析。考虑组内类别(ICU中的“≤11天”和“>11天”)和PO2S身高类别(“<90%”和“≥90%”)的中值。使用针对混杂变量调整的逻辑回归和线性回归模型。结果：在ICU中>11天的患者PO2S≥90％的几率降低了84％（OR：0.16[CI：0.02，0.69]，p=0.005）与ICU中≤11天的患者相比。PO2S增加1％，ICU停留时间减少0.22天（β：-0.22[CI：-0.33，-0.11]，p<0.001)，可能导致减少1.44天。结论：PO2S是评估高海拔地区COVID-19患者ICU住院时间的关键因素，是一种可获得且具有成本效益的措施。应将其用于感染患者，以补充大流行后ICU住院的预后。
