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Abstract：
Objectives: To investigate the outcomes of early balloon kyphoplasty (BKP) intervention compared with late intervention for osteoporotic vertebral fracture (OVF). Background: Osteoporotic vertebral fracture can lead to kyphotic deformity, severe back pain, depression, and disturbances in activities of daily living (ADL). Balloon kyphoplasty has been widely utilized to treat symptomatic OVFs and has proven to be a very effective surgical option for this condition. Furthermore, BKP is relatively a safe and effective method due to its reduced acrylic cement leakage and greater kyphosis correction. Materials and Methods: A retrospective cohort study was conducted at our hospital for patients who underwent BKP for osteoporotic vertebral fractures in the time frame between January 2020 and December 2022. Ninety-nine patients were included in this study, and they were classified into two groups: in total, 36 patients underwent early BKP intervention (EI) at <4 weeks, and 63 patients underwent late BKP intervention (LI) at ≥4 weeks. We performed a clinical, radiological and statistical comparative evaluation for the both groups with a mean follow-up of one year. Results: Adjacent segmental fractures were more frequently observed in the LI group compared to the EI group (33.3% vs. 13.9%, p = 0.034). There was a significant improvement in postoperative vertebral angles in both groups (p = 0.036). The cement volume injected was 7.42 mL in the EI, compared with 6.3 mL in the LI (p = 0.007). The mean surgery time was shorter in the EI, at 30.2 min, compared with 37.1 min for the LI, presenting a significant difference (p = 0.0004). There was no statistical difference in the pain visual analog scale (VAS) between the two groups (p = 0.711), and there was no statistical difference in cement leakage (p = 0.192). Conclusions/Level of Evidence: Early BKP for OVF treatment may achieve better outcomes and fewer adjacent segmental fractures than delayed intervention.
摘要：
目的:探讨早期球囊扩张椎体后凸成形术(BKP)与晚期介入治疗骨质疏松性椎体骨折(OVF)的疗效比较。背景:骨质疏松性椎体骨折可导致后凸畸形,严重的背痛,抑郁症,和日常生活活动（ADL）的干扰。球囊椎体后凸成形术已被广泛用于治疗有症状的OVF，并且已被证明是治疗这种疾病的非常有效的手术选择。此外，BKP是一种相对安全有效的方法，因为它减少了丙烯酸水泥的渗漏和更大的后凸矫正。材料和方法：在我院对在2020年1月至2022年12月期间接受BKP治疗骨质疏松性椎体骨折的患者进行了一项回顾性队列研究。九十九名患者被纳入这项研究，他们分为两组:总共，36例患者在<4周时接受了早期BKP干预（EI），63例患者在≥4周时接受了晚期BKP干预（LI）。我们做了一个临床，对两组进行放射学和统计学比较评价,平均随访一年.结果：与EI组相比，LI组的相邻节段性骨折发生率更高（33.3％vs.13.9%,p=0.034)。两组术后椎体角度均有显著改善(p=0.036)。在EI中注入的水泥体积为7.42mL，与LI中的6.3mL相比（p=0.007）。平均手术时间较短，在30.2分钟，与LI的37.1分钟相比，呈现显著差异(p=0.0004)。两组患者疼痛视觉模拟量表(VAS)差异无统计学意义(p=0.711),水泥渗漏无统计学差异(p=0.192)。结论/证据水平：与延迟干预相比，早期BKP用于OVF治疗可获得更好的结果和更少的相邻节段骨折。
