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Abstract：
BACKGROUND: This study aimed to evaluate the association between the dietary intake of vitamin B complex (thiamine, riboflavin, and niacin) and cervical cancer in Korea.
METHODS: The data from the Korean National Health and Nutrition Examination Survey (KNHANES) from 2010 to 2021 were analyzed, which included 28,306 participants who were categorized into non-cervical cancer and cervical cancer groups. The following dietary intake threshold levels of thiamine, riboflavin, and niacin were identified based on the recommended daily allowances (RDAs): thiamine, 1.1 mg/day; riboflavin, 1.2 mg/day; and niacin, 14 mg/day.
RESULTS: Among 28,306 participants, 27,976 were in the non-cervical cancer group and 330 were in the cervical cancer group. Riboflavin intakes of more than 1.2 mg/day but less than 2.4 mg/day were associated with a significantly reduced risk of cervical cancer, whereas intakes of above 2.4 mg/day were not associated with cervical cancer. Thiamine and niacin intakes were not significantly related to the risk of cervical cancer.
CONCLUSIONS: The results of this study suggest that an intake of riboflavin of 1.2-2.4 mg/day may contribute to a lower risk of cervical cancer.
METHODS: The data from the Korean National Health and Nutrition Examination Survey (KNHANES) from 2010 to 2021 were analyzed, which included 28,306 participants who were categorized into non-cervical cancer and cervical cancer groups. The following dietary intake threshold levels of thiamine, riboflavin, and niacin were identified based on the recommended daily allowances (RDAs): thiamine, 1.1 mg/day; riboflavin, 1.2 mg/day; and niacin, 14 mg/day.
RESULTS: Among 28,306 participants, 27,976 were in the non-cervical cancer group and 330 were in the cervical cancer group. Riboflavin intakes of more than 1.2 mg/day but less than 2.4 mg/day were associated with a significantly reduced risk of cervical cancer, whereas intakes of above 2.4 mg/day were not associated with cervical cancer. Thiamine and niacin intakes were not significantly related to the risk of cervical cancer.
CONCLUSIONS: The results of this study suggest that an intake of riboflavin of 1.2-2.4 mg/day may contribute to a lower risk of cervical cancer.
摘要：
背景：本研究旨在评估膳食摄入复合维生素B（硫胺素，核黄素,和烟酸）和韩国的宫颈癌。
方法：分析了2010年至2021年韩国国家健康与营养检查调查（KNHANES）的数据，其中包括28,306名被分为非宫颈癌和宫颈癌组的参与者.以下膳食摄入硫胺素的阈值水平，核黄素,和烟酸是根据推荐的每日津贴(RDA)确定的：硫胺素，1.1毫克/天；核黄素，1.2毫克/天；烟酸，14mg/天。
结果：在28,306名参与者中，非宫颈癌组27,976例，宫颈癌组330例。核黄素摄入量超过1.2毫克/天但低于2.4毫克/天与宫颈癌风险显着降低相关。而超过2.4mg/天的摄入量与宫颈癌无关。硫胺素和烟酸的摄入量与宫颈癌的风险没有显着相关性。
结论：这项研究的结果表明，每天摄入1.2-2.4mg的核黄素可能有助于降低宫颈癌的风险。
方法：分析了2010年至2021年韩国国家健康与营养检查调查（KNHANES）的数据，其中包括28,306名被分为非宫颈癌和宫颈癌组的参与者.以下膳食摄入硫胺素的阈值水平，核黄素,和烟酸是根据推荐的每日津贴(RDA)确定的：硫胺素，1.1毫克/天；核黄素，1.2毫克/天；烟酸，14mg/天。
结果：在28,306名参与者中，非宫颈癌组27,976例，宫颈癌组330例。核黄素摄入量超过1.2毫克/天但低于2.4毫克/天与宫颈癌风险显着降低相关。而超过2.4mg/天的摄入量与宫颈癌无关。硫胺素和烟酸的摄入量与宫颈癌的风险没有显着相关性。
结论：这项研究的结果表明，每天摄入1.2-2.4mg的核黄素可能有助于降低宫颈癌的风险。
