{Reference Type}: Journal Article
{Title}: Optimal Dietary Intake of Riboflavin Associated with Lower Risk of Cervical Cancer in Korea: Korean National Health and Nutrition Examination Survey 2010-2021.
{Author}: Lee SM;Seol A;Cho HW;Min KJ;Lee S;Hong JH;Song JY;Lee JK;Lee NW;
{Journal}: Life (Basel)
{Volume}: 14
{Issue}: 4
{Year}: 2024 Apr 20
{Factor}: 3.251
{DOI}: 10.3390/life14040529
{Abstract}: <B>BACKGROUND: </B>This study aimed to evaluate the association between the dietary intake of vitamin B complex (thiamine, riboflavin, and niacin) and cervical cancer in Korea.<BR><B>METHODS: </B>The data from the Korean National Health and Nutrition Examination Survey (KNHANES) from 2010 to 2021 were analyzed, which included 28,306 participants who were categorized into non-cervical cancer and cervical cancer groups. The following dietary intake threshold levels of thiamine, riboflavin, and niacin were identified based on the recommended daily allowances (RDAs): thiamine, 1.1 mg/day; riboflavin, 1.2 mg/day; and niacin, 14 mg/day.<BR><B>RESULTS: </B>Among 28,306 participants, 27,976 were in the non-cervical cancer group and 330 were in the cervical cancer group. Riboflavin intakes of more than 1.2 mg/day but less than 2.4 mg/day were associated with a significantly reduced risk of cervical cancer, whereas intakes of above 2.4 mg/day were not associated with cervical cancer. Thiamine and niacin intakes were not significantly related to the risk of cervical cancer.<BR><B>CONCLUSIONS: </B>The results of this study suggest that an intake of riboflavin of 1.2-2.4 mg/day may contribute to a lower risk of cervical cancer.