Abstract:
The phrase \"Bench-to-Bedside\" is a well-known phrase in medicine, highlighting scientific discoveries that directly translate to impacting patient care. Key examples of translational research include identification of key molecular targets in diseases and development of diagnostic laboratory tests for earlier disease detection. Bridging these scientific advances to the bedside/clinic has played a meaningful impact in numerous patient lives. The spaceflight environment poses a unique opportunity to also make this impact; the nature of harsh extraterrestrial conditions and medically austere and remote environments push for cutting-edge technology innovation. Many of these novel technologies built for the spaceflight environment also have numerous benefits for human health on Earth. In this manuscript, we focus on \"Spaceflight-to-Eye Clinic\" and discuss technologies built for the spaceflight environment that eventually helped to optimize ophthalmic health on Earth (e.g., LADAR for satellite docking now utilized in eye-tracking technology for LASIK). We also discuss current technology research for spaceflight associated neuro-ocular syndrome (SANS) that may also be applied to terrestrial ophthalmic health. Ultimately, various advances made to enable to the future of space exploration have also advanced the ophthalmic health of individuals on Earth.
摘要:
短语“长凳到床边”是医学中的一个众所周知的短语,强调直接转化为影响患者护理的科学发现。翻译研究的关键例子包括识别疾病中的关键分子靶标以及开发用于早期疾病检测的诊断实验室测试。将这些科学进步与床边/诊所联系起来,对许多患者的生活产生了有意义的影响。航天环境提供了一个独特的机会,也使这种影响;恶劣的地外条件和医学上严峻和偏远的环境推动尖端技术创新的性质。许多为航天环境建造的这些新技术也对地球上的人类健康有许多好处。在这份手稿中,我们专注于“太空飞行到眼科诊所”,并讨论为太空飞行环境建造的技术,这些技术最终有助于优化地球上的眼科健康(例如,用于卫星对接的LADAR现在用于LASIK的眼动跟踪技术)。我们还讨论了航天相关神经眼综合征(SANS)的当前技术研究,该技术也可能适用于地面眼科健康。最终,为实现太空探索的未来而取得的各种进展也促进了地球上个人的眼科健康。