PDF(Pubmed)
Abstract：
Myotonic dystrophy type I (MDI) is the most common muscular dystrophy in adults. The main objectives of this study were to determine the prevalence of MDI in the Community of Madrid (CM) (Spain) and to analyze the use of public healthcare services; a population-based cross-sectional descriptive study was carried out on patients with MDI in CM and data were obtained from a population-based registry (2010-2017). A total of 1101 patients were studied (49.1% women) with average age of 47.8 years; the prevalence of MDI was 14.4/100,000 inhabitants. In the women lineal regression model for hospital admissions, being in the fourth quartile of the deprivation index, was a risk factor (regression coef (rc): 0.80; 95%CI 0.25-1.37). In the overall multiple lineal regression model for primary health care (PHC) attendance, being a woman increased the probability of having a higher number of consultations (rc: 3.99; 95%CI: 3.95-5.04), as did being in the fourth quartile of the deprivation index (rc: 2.10; 95%CI: 0.58-3.63); having received influenza vaccines was a protective factor (rc: -0.46; 95%CI: -0.66-(-0.25)). The prevalence of MDI in the CM is high compared to other settings. Moreover, having any level of risk stratification of becoming ill (high, medium or low) has a positive association with increased PHC consultations and hospital admissions.
摘要：
强直性肌营养不良I型(MDI)是成人中最常见的肌营养不良。这项研究的主要目标是确定马德里社区（CM）（西班牙）中MDI的患病率，并分析公共医疗服务的使用；对CM中MDI患者进行了基于人群的横断面描述性研究，数据来自基于人群的注册表（2010-2017）。总共研究了1101名患者（49.1％的女性），平均年龄为47.8岁；MDI的患病率为14.4/100,000居民。在住院的女性线性回归模型中，处于剥夺指数的第四个四分位数，是一个危险因素(回归系数(rc)：0.80；95CI0.25-1.37)。在初级卫生保健(PHC)出勤的总体多元线性回归模型中，作为一名女性增加了进行更多咨询的可能性(rc:3.99;95CI:3.95-5.04)，在剥夺指数的第四个四分位数中也是如此(rc:2.10;95CI:0.58-3.63);接种过流感疫苗是保护因素(rc:-0.46;95CI:-0.66-(-0.25)).与其他设置相比，CM中MDI的患病率较高。此外，有任何程度的患病风险分层(高，中等或低)与PHC咨询和住院人数增加呈正相关。
