Abstract：
The history of nasal polyposis originates even before Hippocrates described a nasal mass that he likened to a sea polyp. References to sinonasal disease and treatment can be found in ancient texts, such as the Ebers Papyrus and the Edwin Smith Papyrus of Ancient Egypt, as well as in the foundational texts of Ayurvedic medicine. Greek philosophers marked a significant shift away from the belief that illness was a result of divine intervention and embraced medical theory. Over the subsequent millennia, the understanding of nasal polyposis expanded, resulting in notable progress in surgical procedures and medical treatments. However, the complex pathophysiology of this condition remained enigmatic until breakthroughs in basic science and immunology. This historical journey takes us from the tomb of the first rhinologist in 2500 BC to the development of immune-modulating biologics.
摘要：
鼻息肉病的历史甚至在希波克拉底描述他比作海息肉的鼻肿块之前就开始了。在古代文献中可以找到对鼻窦疾病和治疗的引用，例如古埃及的埃伯斯纸莎草和埃德温·史密斯纸莎草，以及阿育吠陀医学的基础文本。希腊哲学家标志着一个重大转变，即疾病是神圣干预和接受医学理论的结果。在随后的几千年里，扩大了对鼻息肉病的认识，在外科手术和药物治疗方面取得了显著进展。然而,在基础科学和免疫学取得突破之前，这种情况的复杂病理生理学仍然是神秘的。这一历史旅程将我们从公元前2500年第一位鼻学家的坟墓带到免疫调节生物制剂的开发。
