PDF(Pubmed)
Abstract：
We evaluated Q fever prevalence in blood donors and assessed the epidemiologic features of the disease in Israel in 2021. We tested serum samples for Coxeilla burnetii phase I and II IgG using immunofluorescent assay, defining a result of >200 as seropositive. We compared geographic and demographic data. We included 1,473 participants; 188 (12.7%) were seropositive. The calculated sex- and age-adjusted national seroprevalence was 13.9% (95% CI 12.2%-15.7%). Male sex and age were independently associated with seropositivity (odds ratio [OR] 1.6, 95% CI 1.1-2.2; p = 0.005 for male sex; OR 1.2, 95% CI 1.01-1.03; p<0.001 for age). Residence in the coastal plain was independently associated with seropositivity for Q fever (OR 1.6, 95% CI 1.2-2.3; p<0.001); residence in rural and farming regions was not. Q fever is highly prevalent in Israel. The unexpected spatial distribution in the nonrural coastal plain suggests an unrecognized mode of transmission.
摘要：
我们评估了2021年以色列献血者的Q热患病率，并评估了该疾病的流行病学特征。我们使用免疫荧光测定法测试了血清样品的CoxeillaI期和II期IgG，将>200的结果定义为血清阳性。我们比较了地理和人口数据。我们纳入了1,473名参与者；188名（12.7%）血清呈阳性。计算的性别和年龄调整后的全国血清阳性率为13.9％（95％CI12.2％-15.7％）。男性性别和年龄与血清阳性独立相关（优势比[OR]1.6，95％CI1.1-2.2；男性p=0.005；OR1.2，95％CI1.01-1.03；年龄p<0.001）。居住在沿海平原与Q热的血清阳性独立相关（OR1.6，95％CI1.2-2.3；p<0.001）；居住在农村和农业地区则没有。Q热在以色列非常普遍。非农村沿海平原的意外空间分布表明了一种无法识别的传播方式。
