PDF(Pubmed)
Abstract：
Eosinophilic fasciitis can be a debilitating diagnosis and is often delayed given its similarities to other sclerotic conditions including morphea, such as bound-down indurated skin and inflammation and sclerotic thickening of tissue layers on histopathology. Delaying treatment can lead to joint contracture and residual hardness in skin which has both cosmetic and functional implications. Therefore, finding the definitive diagnosis and differentiating from other sclerotic diseases is important early in the disease course. We present a case of a 77-year-old female with a generalized rash on her back and extremities, and progressive symptoms of pain, joint contractures, and limited movement, which highlights the challenges in diagnosis and management given clinical and histological parallels between eosinophilic fasciitis and morphea.
摘要：
嗜酸性筋膜炎可能是一种使人衰弱的诊断，并且由于其与其他硬化性疾病（包括硬皮病）的相似性，通常会延迟。如在组织病理学上的结合-下硬化的皮肤和组织层的炎症和硬化增厚。延迟治疗可导致关节挛缩和皮肤残余硬度，具有美容和功能意义。因此,在病程早期发现明确的诊断和与其他硬化性疾病的鉴别具有重要意义。我们介绍了一个77岁的女性，她的背部和四肢出现了全身性皮疹，和进行性疼痛症状，关节挛缩,和有限的运动，鉴于嗜酸细胞性筋膜炎和硬皮病之间的临床和组织学相似之处，这突出了诊断和治疗方面的挑战。
