PDF(Pubmed)
Abstract：
Bone giant cell tumors (GCTs) are rare, non-cancerous tumors that mostly affect the meta-epiphyseal region of long bones in the legs and arms. We are reporting a case of GCT of bone of a 14-year-old male; it usually occurs in the age group of 20-40 years. The presence of multinucleated giant cells and stromal cells in the proximal diaphysis of the left tibia serves as a distinguishing characteristic. The majority of GCTs are benign; they have the potential to induce bone loss and can be locally aggressive. Treatment options often include surgery, and in some cases, medications like denosumab may be used to help shrink the tumor or manage recurrent cases.
摘要：
骨巨细胞瘤（GCT）很少见，非癌性肿瘤，主要影响腿部和手臂长骨的骨phy区。我们正在报告一例14岁男性的骨GCT；它通常发生在20-40岁的年龄段。左胫骨近端骨干中多核巨细胞和基质细胞的存在是一个明显的特征。大多数GCT是良性的;它们具有诱导骨丢失的潜力并且可以是局部侵袭性的。治疗选择通常包括手术，在某些情况下,denosumab等药物可用于帮助缩小肿瘤或治疗复发病例。
