PDF(Pubmed)
Abstract：
Resting-state fMRI (rs-fMRI) has emerged as an alternative method to study brain function in human and animal models. In humans, it has been widely used to study psychiatric disorders including schizophrenia, bipolar disorder, autism spectrum disorders, and attention deficit hyperactivity disorders. In this review, rs-fMRI and its advantages over task based fMRI, its currently used analysis methods, and its application in psychiatric disorders using different analysis methods are discussed. Finally, several limitations and challenges of rs-fMRI applications are also discussed.
摘要：
静息状态功能磁共振成像（rs-fMRI）已成为研究人类和动物模型中脑功能的替代方法。在人类中,它已被广泛用于研究包括精神分裂症在内的精神疾病，双相情感障碍,自闭症谱系障碍，和注意力缺陷多动障碍。在这次审查中,rs-fMRI及其相对于基于任务的fMRI的优势，其目前使用的分析方法，并对不同分析方法在精神疾病中的应用进行了讨论。最后,还讨论了rs-fMRI应用的一些局限性和挑战。
