AI / ML 衍生的剪接转换寡核苷酸的开发和验证。
关键词: Alternative Splicing Machine Learning Splice-Switching Oligonucleotides Splicing Factors Triple Negative Breast Cancer
Mesh : Humans Machine Learning Triple Negative Breast Neoplasms / genetics Artificial Intelligence Alternative Splicing Cell Line, Tumor Nedd4 Ubiquitin Protein Ligases / genetics metabolism RNA Precursors / genetics metabolism Cell Proliferation / drug effects genetics RNA Splicing Factors / genetics metabolism Oligonucleotides, Antisense / genetics Cell Movement / genetics Spliceosomes / metabolism genetics Oligonucleotides / genetics Female
来 源:
DOI:10.1038/s44320-024-00034-9
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