Abstract：
Distinguishing key morphologic features and understanding the pathophysiology of common cutaneous manifestations of hematologic disorders is essential to ensure prompt and appropriate treatment. In fact, classic cutaneous signs may provide the first clue to the diagnosis of an underlying hematologic disease. Disorders of coagulation, vascular abnormalities, or cutaneous infiltration and deposition are responsible for the underlying pathophysiology of cutaneous manifestations in the majority of cases. Hematologists often feel ill-equipped in identifying morphologic changes in the skin. Thus, the purpose of this review is to provide a comprehensive overview of classic cutaneous manifestations and diagnostic considerations of the associated hematologic conditions. Though there is a specific focus on non-malignant disorders, those straddling the spectrum of malignancy are also discussed. In many disease states, the skin may serve as an important marker of an emerging hematologic disorder, so close collaboration and multidisciplinary input remain essential to provide optimal and timely care for these patients.
摘要：
区分关键的形态学特征并了解血液病的常见皮肤表现的病理生理学对于确保及时和适当的治疗至关重要。事实上,经典的皮肤体征可能为潜在血液病的诊断提供了第一线索.凝血障碍，血管异常,在大多数情况下，或皮肤浸润和沉积是皮肤表现的潜在病理生理学原因。血液科医师经常感到在识别皮肤的形态变化方面不充分。因此，本综述的目的是全面概述经典的皮肤表现和相关血液学疾病的诊断考虑.尽管非恶性疾病特别关注，还讨论了跨越恶性肿瘤范围的问题。在许多疾病状态下，皮肤可能是新出现的血液系统疾病的重要标志，因此，密切合作和多学科投入对于为这些患者提供最佳和及时的护理仍然至关重要。
