Abstract：
There is limited published data regarding cardiovascular disease in nondomestic felid populations. To address this knowledge gap, necropsy cases of tigers and lions with representative myocardial samples submitted to a diagnostic laboratory were histologically assessed with hematoxylin and eosin and Sirius red stains. A total of 32 submissions (15 tigers, 17 lions) were identified in a 4-year period. All tigers and lions had some degree of coronary artery lesions in the left ventricle and/or interventricular septum. Major findings included moderate to marked arteriosclerosis in 8 tigers (53%) and 4 lions (24%) and moderate to marked perivascular fibrosis in 10 tigers (67%) and 9 lions (53%). Moreover, 10 tigers (67%) and 8 lions (47%) had coronary artery lesions with variable degrees of perivascular cardiomyocyte degeneration and/or loss. To our knowledge, this is the first report describing coronary artery pathology in captive tigers and lions.
摘要：
关于非家庭猫人群心血管疾病的公开数据有限。为了解决这个知识差距，用苏木精和曙红和天狼星红染色对提交给诊断实验室的具有代表性的心肌样本的老虎和狮子的尸检病例进行组织学评估。共有32份意见书(15只老虎,在4年内发现了17只狮子）。所有老虎和狮子的左心室和/或室间隔都有一定程度的冠状动脉病变。主要发现包括8只老虎（53％）和4只狮子（24％）的中度至明显的动脉硬化，以及10只老虎（67％）和9只狮子（53％）的中度至明显的血管周围纤维化。此外，10只老虎（67％）和8只狮子（47％）患有冠状动脉病变，血管周围心肌细胞变性和/或丢失程度不同。据我们所知,这是第一篇描述圈养老虎和狮子冠状动脉病变的报告。
