Abstract：
Endophthalmitis is a severe form of purulent inflammation caused by the infection of the intraocular tissues or fluids. This infection infrequently occurs through endogenous routes, which are often correlated with major risk factors. Escherichia coli, a gram-negative rod, can cause endophthalmitis through hematogenous spread. We here report a 59-year-old man who presented to our service with acute visual impairment in his left eye, preceded by floaters. He was taking sirolimus and azathioprine for a transplanted kidney, had undergone catheterization for bladder atresia, and had a history of recurrent E. coli urinary tract infections. On evaluation, the left eye exhibited visual acuity of hand motion, anterior chamber reaction (3+/4+), and intense vitritis (4+/4+) with white flake clusters, which prevented appropriate retinal evaluation. Pars plana vitrectomy was performed, and the culture yielded E. coli. The present case highlights the importance of identifying the signs and symptoms of infection early so that diagnosis and treatment of endophthalmitis can be promptly initiated.
摘要：
眼内炎是由眼内组织或液体感染引起的严重形式的化脓性炎症。这种感染很少通过内源性途径发生，通常与主要风险因素相关。大肠杆菌,革兰氏阴性棒,可通过血行传播引起眼内炎。我们在这里报告一名59岁的男子，他的左眼患有急性视力障碍，前面是漂浮物。他正在服用西罗莫司和硫唑嘌呤进行肾脏移植，接受过膀胱闭锁导管插入术,有复发性大肠杆菌尿路感染史。关于评估，左眼表现出手部动作的视力，前房反应（3+/4+），和强烈的玻璃体炎（4+/4+）与白色薄片簇，这阻止了适当的视网膜评估。进行了平坦部玻璃体切除术，培养物产生大肠杆菌。本病例强调了早期识别感染体征和症状的重要性，以便及时开始诊断和治疗眼内炎。
