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Abstract：
Haploid cells are a kind of cells with only one set of chromosomes. Compared with traditional diploid cells, haploid cells have unique advantages in gene screening and drug-targeted therapy, due to their phenotype being equal to the genotype. Embryonic stem cells are a kind of cells with strong differentiation potential that can differentiate into various types of cells under specific conditions in vitro. Therefore, haploid embryonic stem cells have the characteristics of both haploid cells and embryonic stem cells, which makes them have significant advantages in many aspects, such as reproductive developmental mechanism research, genetic screening, and drug-targeted therapy. Consequently, establishing haploid embryonic stem cell lines is of great significance. This paper reviews the progress of haploid embryonic stem cell research and briefly discusses the applications of haploid embryonic stem cells.
摘要：
单倍体细胞是一种只有一组染色体的细胞。与传统的二倍体细胞相比，单倍体细胞在基因筛选和药物靶向治疗方面具有独特的优势,由于它们的表型等于基因型。胚胎干细胞是一种具有很强分化潜能的细胞,在体外特定条件下可以分化为各种类型的细胞。因此,单倍体胚胎干细胞同时具有单倍体细胞和胚胎干细胞的特性,这使得它们在许多方面都有显著的优势，如生殖发育机制研究，遗传筛选,和药物靶向治疗。因此,建立单倍体胚胎干细胞系具有重要意义。本文综述了单倍体胚胎干细胞的研究进展，并简要讨论了单倍体胚胎干细胞的应用。
