PDF(Pubmed)
Abstract：
BACKGROUND: Indocyanine green fluorescence angiography, a validated noninvasive imaging technique, is used to assess tissue vascularization. Here, we report three infant patients who underwent intraoperative indocyanine green fluorescence angiography and suffered from postoperative complications caused by the lack of weak fluorescent intestinal resection and assessed residual intestinal perfusion.
METHODS: We observed the clinical characteristics and operative findings of patients treated from January 2022 to December 2022. Indocyanine green (0.5 mg/kg) was intravenously injected. The first patient was a 29-day-old girl with surgical necrotizing enterocolitis who underwent intraoperative indocyanine green fluorescence angiography at the first- and second-look operations. The proximal jejunum was difficult to diagnose to detect blood flow during the second-look operation. The second patient was a 32-day-old boy with surgical necrotizing enterocolitis. A part of the antimesenteric mucosa of the patient that exhibited weak fluorescence was preserved; however, it formed postoperative hematomas. The third patient was a 30-day-old boy with midgut volvulus. Weak fluorescence in the intestinal wall was observed 5 cm of the small intestine from the ileocecal valve was preserved, but it formed a stricture, and the patient underwent ileocecal resection after 30 days.
CONCLUSIONS: Weak fluorescence in the intestine in infants by performing indocyanine green fluorescence angiography is associated with a high risk of non-recovering ischemic lesions and postoperative complications.
METHODS: We observed the clinical characteristics and operative findings of patients treated from January 2022 to December 2022. Indocyanine green (0.5 mg/kg) was intravenously injected. The first patient was a 29-day-old girl with surgical necrotizing enterocolitis who underwent intraoperative indocyanine green fluorescence angiography at the first- and second-look operations. The proximal jejunum was difficult to diagnose to detect blood flow during the second-look operation. The second patient was a 32-day-old boy with surgical necrotizing enterocolitis. A part of the antimesenteric mucosa of the patient that exhibited weak fluorescence was preserved; however, it formed postoperative hematomas. The third patient was a 30-day-old boy with midgut volvulus. Weak fluorescence in the intestinal wall was observed 5 cm of the small intestine from the ileocecal valve was preserved, but it formed a stricture, and the patient underwent ileocecal resection after 30 days.
CONCLUSIONS: Weak fluorescence in the intestine in infants by performing indocyanine green fluorescence angiography is associated with a high risk of non-recovering ischemic lesions and postoperative complications.
摘要：
背景：吲哚菁绿荧光血管造影，一种经过验证的非侵入性成像技术，用于评估组织血管化。这里,我们报告了3例接受术中吲哚菁绿荧光血管造影的婴儿患者，这些患者因缺乏弱荧光肠切除而出现术后并发症，并评估了残余肠灌注。
方法：我们观察了2022年1月至2022年12月接受治疗的患者的临床特征和手术结果。静脉注射吲哚菁绿(0.5mg/kg)。第一位患者是一名29天大的女孩，患有手术坏死性小肠结肠炎，在第一眼和第二眼手术中接受了术中吲哚菁绿荧光血管造影。在第二次手术期间，近端空肠难以诊断以检测血流。第二名患者是一名32天大的男孩，患有手术坏死性小肠结肠炎。保留了患者表现出微弱荧光的部分抗肠系膜粘膜；但是，术后形成血肿。第三位患者是一个30天大的男孩，患有中肠扭转。在肠壁中观察到微弱的荧光，距回盲阀5cm的小肠被保留，但是它形成了一个狭窄，30天后患者接受回盲部切除术。
结论：通过实施吲哚菁绿荧光血管造影术在婴儿肠道中的弱荧光与未恢复的缺血性病变和术后并发症的高风险相关。
方法：我们观察了2022年1月至2022年12月接受治疗的患者的临床特征和手术结果。静脉注射吲哚菁绿(0.5mg/kg)。第一位患者是一名29天大的女孩，患有手术坏死性小肠结肠炎，在第一眼和第二眼手术中接受了术中吲哚菁绿荧光血管造影。在第二次手术期间，近端空肠难以诊断以检测血流。第二名患者是一名32天大的男孩，患有手术坏死性小肠结肠炎。保留了患者表现出微弱荧光的部分抗肠系膜粘膜；但是，术后形成血肿。第三位患者是一个30天大的男孩，患有中肠扭转。在肠壁中观察到微弱的荧光，距回盲阀5cm的小肠被保留，但是它形成了一个狭窄，30天后患者接受回盲部切除术。
结论：通过实施吲哚菁绿荧光血管造影术在婴儿肠道中的弱荧光与未恢复的缺血性病变和术后并发症的高风险相关。
