Abstract：
Bovine Trypanosomiasis and other infectious diseases cause relevant loss for the livestock industry impacting productive/reproductive indices. This study intended to better understand the frequency, seasonality, and profile of infections associated with Bovine Trypanosomiasis. A total of 1443 serum samples were screened for T. vivax infection and other infectious diseases: Neosporosis, Leptospirosis, Bovine Leukosis Virus infection/(BLV), Infectious Bovine Rhinotracheitis/(IBR) or Bovine Viral Diarrhea/(BVD). Distinct methods were used for screening and diagnosis: immunofluorescence assay (Trypanosomiasis), ELISA (Neosporosis,BLV,IBR,BVD) and microscopic agglutination test (Leptospirosis). Our findings demonstrated that the seropositivity for Trypanosomiasis=57% was similar to Neosporosis=55%, higher than Leptospirosis=39% and BVL=34%, but lower than IBR=88% and BVD=71%. The seropositivity for Trypanosomiasis was higher in the autumn and lower in the winter. Regardless the season, the IBR seropositivity (min=73%;max=95%) was higher than Trypanosomiasis (min=48%;max=68%). Moreover, Neosporosis (min=71%;max=100%) and BVD (min=65%;max=76%) were more frequent than Trypanosomiasis in the summer, winter and spring. The diagnosis outcome revealed that Trypanosomiasis&IBR=43% and Trypanosomiasis&Neosporosis=35% were the most frequent co-infections with higher seropositivity in the autumn (58%) and summer (80%), respectively. Noteworthy, high seropositivity to Trypanosomiasis&BVD was registered in the autumn (46%). Together, our data re-enforce the relevance of differential diagnosis between Trypanosomiasis with other bovine infectious diseases and that differences in the seasonality profile is a relevant aspect to be considered while selecting the differential diagnosis to be applied.
摘要：
牛锥虫病和其他传染病对影响生产/生殖指数的畜牧业造成相关损失。这项研究旨在更好地了解频率，季节性,和与牛锥虫病相关的感染概况。共筛选出1443份血清样本进行间日疟原虫感染和其他感染性疾病：新孢子虫病，钩端螺旋体病,牛白血病病毒感染/（BLV），牛传染性鼻支气管炎/（IBR）或牛病毒性腹泻/（BVD）。不同的方法用于筛查和诊断：免疫荧光测定（锥虫病），ELISA（新孢子虫病，BLV,IBR,BVD）和显微镜凝集试验（钩端螺旋体病）。我们的研究结果表明，锥虫病=57％的血清阳性与新孢子虫病=55％相似，高于钩端螺旋体病=39%和BVL=34%，但低于IBR=88%和BVD=71%。锥虫病的血清阳性率在秋季较高，在冬季较低。不管是什么季节,IBR血清阳性(min=73%;max=95%)高于锥虫病(min=48%;max=68%).此外，在夏季，新孢子虫病（min=71％；max=100％）和BVD（min=65％；max=76％）比锥虫病更频繁，冬天和春天。诊断结果显示，锥虫病和IBR=43％，锥虫病和新孢子虫病=35％是最常见的共感染，在秋季（58％）和夏季（80％）具有较高的血清阳性，分别。值得注意的是,秋季对锥虫病和BVD的血清呈高阳性（46％）。一起,我们的数据证实了锥虫病与其他牛感染性疾病之间的鉴别诊断的相关性,并且季节性特征的差异是选择鉴别诊断时需要考虑的一个相关方面.
