Abstract:
Etomidate is a nonbarbiturate sedative derived from imidazole. Prolonged and excessive use of etomidate can lead to the suppression of adrenocortical function, myoclonus, and even death. This report describes a rare case of a 47-year-old man who died from acute intoxication after oral ingestion of liquid containing etomidate. The cause of death was conclusively attributed to etomidate based on a comprehensive investigation, including autopsy, histopathological examination, toxicological analysis, and biochemical analysis. This is the first reported case of a fatality solely resulting from the oral ingestion of etomidate, which can provide valuable insights for future forensic investigations involving etomidate poisoning. Therefore, it is imperative to share this case with the scientific community.
摘要:
依托咪酯是源自咪唑的非巴比妥镇静剂。长期和过度使用依托咪酯可导致肾上腺皮质功能的抑制,肌阵鸣,甚至死亡。该报告描述了一例罕见的病例,一例47岁的男子因口服含依托咪酯的液体而死于急性中毒。根据全面调查,死因最终归因于依托咪酯,包括尸检,组织病理学检查,毒理学分析,和生化分析。这是首次报道的仅因口服依托咪酯引起的死亡病例,这可以为未来涉及依托咪酯中毒的法医调查提供有价值的见解。因此,必须与科学界分享这一案例。