PDF(Pubmed)
Abstract：
BACKGROUND: Sleep disorders are often complained by cancer patients and can last years after the end of therapies, leading to different negative consequences. Non-pharmacological strategies such as exercise interventions may be considered to counteract this phenomenon. The literature supports the beneficial effects of aerobic training (AT), while evidence on resistance training (RT) is scarce. Accordingly, our systematic review aims to investigate the potential novel effect of RT on sleep outcomes in cancer survivors.
METHODS: The literature search was conducted on MEDLINE (Pubmed), Web of Science, Scopus, and Cochrane Central Register of Controlled Trials databases, including only randomized controlled trials (RCTs). The screening procedure was conducted using the web-based software COVIDENCE. Sleep outcomes assessed through self-reported questionnaires or objective sleep measurements were extracted from RCTs recruiting cancer survivors of any age and gender, on or off treatment. The risk of bias (RoB) for each study was assessed using the Cochrane RoB 2 tool for RCTs. Meta-analytic syntheses were performed on sleep quality and insomnia.
RESULTS: A total of 21 studies were included in the review. Considering the mean percentage differences of all studies combined, promising positive results were found after combined aerobic and resistance exercise program (COMB) for sleep quality (-19%) and sleep disturbance (-17.3%). The meta-analysis results showed significant improvement for both sleep quality and insomnia (d = 0.28, SE: 0.11, Z = 2.51, p < 0.01, 95% CI: 0.07-0.49 and d = 0.43, SE: 0.20, Z = 2.18, p = 0.029, 95% CI: 0.07-0.49, respectively).
CONCLUSIONS: RT interventions of 60 minutes per session, performed 2-3 times a week for 12 weeks, with exercise intensity ranging from 60% to 80% of one-repetition maximum can be administered to cancer survivors, aiming to improve sleep outcomes.
METHODS: The literature search was conducted on MEDLINE (Pubmed), Web of Science, Scopus, and Cochrane Central Register of Controlled Trials databases, including only randomized controlled trials (RCTs). The screening procedure was conducted using the web-based software COVIDENCE. Sleep outcomes assessed through self-reported questionnaires or objective sleep measurements were extracted from RCTs recruiting cancer survivors of any age and gender, on or off treatment. The risk of bias (RoB) for each study was assessed using the Cochrane RoB 2 tool for RCTs. Meta-analytic syntheses were performed on sleep quality and insomnia.
RESULTS: A total of 21 studies were included in the review. Considering the mean percentage differences of all studies combined, promising positive results were found after combined aerobic and resistance exercise program (COMB) for sleep quality (-19%) and sleep disturbance (-17.3%). The meta-analysis results showed significant improvement for both sleep quality and insomnia (d = 0.28, SE: 0.11, Z = 2.51, p < 0.01, 95% CI: 0.07-0.49 and d = 0.43, SE: 0.20, Z = 2.18, p = 0.029, 95% CI: 0.07-0.49, respectively).
CONCLUSIONS: RT interventions of 60 minutes per session, performed 2-3 times a week for 12 weeks, with exercise intensity ranging from 60% to 80% of one-repetition maximum can be administered to cancer survivors, aiming to improve sleep outcomes.
摘要：
背景：癌症患者经常抱怨睡眠障碍，并且可以在治疗结束后持续数年，导致不同的负面后果。可以考虑诸如运动干预的非药理学策略来抵消这种现象。文献支持有氧训练(AT)的有益效果，而阻力训练（RT）的证据很少。因此，我们的系统综述旨在研究RT对癌症幸存者睡眠结局的潜在新影响.
方法：在MEDLINE（Pubmed）上进行了文献检索，WebofScience,Scopus,和Cochrane中央对照试验注册数据库，仅包括随机对照试验（RCT）。使用基于网络的软件COVIDENCE进行筛选程序。从招募任何年龄和性别的癌症幸存者的RCT中提取通过自我报告问卷或客观睡眠测量评估的睡眠结果。开或关治疗。使用CochraneRoB2工具进行RCT评估每个研究的偏倚风险（RoB）。对睡眠质量和失眠进行Meta分析。
结果：本综述共纳入21项研究。考虑到所有研究的平均百分比差异，在有氧运动和抗阻运动计划（COMB）的睡眠质量（-19％）和睡眠障碍（-17.3％）相结合后，发现了有希望的积极结果。荟萃分析结果显示睡眠质量和失眠均有显著改善(d=0.28,SE:0.11,Z=2.51,p<0.01,95%CI:0.07-0.49,d=0.43,SE:0.20,Z=2.18,p=0.029,95%CI:0.07-0.49)。
结论：每次60分钟的RT干预，每周进行2-3次，持续12周，运动强度范围从60%到80%的一个重复的最大可以给予癌症幸存者，旨在改善睡眠结果。
方法：在MEDLINE（Pubmed）上进行了文献检索，WebofScience,Scopus,和Cochrane中央对照试验注册数据库，仅包括随机对照试验（RCT）。使用基于网络的软件COVIDENCE进行筛选程序。从招募任何年龄和性别的癌症幸存者的RCT中提取通过自我报告问卷或客观睡眠测量评估的睡眠结果。开或关治疗。使用CochraneRoB2工具进行RCT评估每个研究的偏倚风险（RoB）。对睡眠质量和失眠进行Meta分析。
结果：本综述共纳入21项研究。考虑到所有研究的平均百分比差异，在有氧运动和抗阻运动计划（COMB）的睡眠质量（-19％）和睡眠障碍（-17.3％）相结合后，发现了有希望的积极结果。荟萃分析结果显示睡眠质量和失眠均有显著改善(d=0.28,SE:0.11,Z=2.51,p<0.01,95%CI:0.07-0.49,d=0.43,SE:0.20,Z=2.18,p=0.029,95%CI:0.07-0.49)。
结论：每次60分钟的RT干预，每周进行2-3次，持续12周，运动强度范围从60%到80%的一个重复的最大可以给予癌症幸存者，旨在改善睡眠结果。
