Abstract：
Brain arteriovenous malformations (bAVMs) are complex, and rare arteriovenous shunts that present with a wide range of signs and symptoms, with intracerebral hemorrhage being the most severe. Despite prior societal position statements, there is no consensus on the management of these lesions. ARISE (Aneurysm/bAVM/cSDH Roundtable Discussion With Industry and Stroke Experts) was convened to discuss evidence-based approaches and enhance our understanding of these complex lesions. ARISE identified the need to develop scales to predict the risk of rupture of bAVMs, and the use of common data elements to perform prospective registries and clinical studies. Additionally, the group underscored the need for comprehensive patient management with specialized centers with expertise in cranial and spinal microsurgery, neurological endovascular surgery, and stereotactic radiosurgery. The collection of prospective multicenter data and gross specimens was deemed essential for improving bAVM characterization, genetic evaluation, and phenotyping. Finally, bAVMs should be managed within a multidisciplinary framework, with clinical studies and research conducted collaboratively across multiple centers, harnessing the collective expertise and centralization of resources.
摘要：
脑动静脉畸形（bAVM）很复杂，和罕见的动静脉分流，表现出广泛的体征和症状，脑出血是最严重的.尽管之前有社会立场声明，对于这些病变的处理尚无共识.召开ARISE（动脉瘤/bAVM/cSDH与行业和中风专家的圆桌会议讨论），讨论基于证据的方法，并增强我们对这些复杂病变的理解。ARISE确定需要开发量表来预测bAVM破裂的风险，以及使用通用数据元素进行前瞻性登记和临床研究。此外,该小组强调需要与具有颅骨和脊柱显微外科专业知识的专业中心进行全面的患者管理，神经血管内手术,和立体定向放射外科.收集前瞻性多中心数据和总体样本被认为对改善bAVM表征至关重要，遗传评估,和表型。最后,bAVM应该在多学科框架内管理，通过在多个中心合作进行的临床研究和研究，利用集体专业知识和资源集中。
