Abstract：
Medication adherence is of utmost importance in achieving the desired therapeutic outcome and effectively managing seizures in patients with epilepsy (PWE). It is imperative to recognize self-esteem as a psychological determinant that potentially influences the optimal compliance with anti-seizure medications (ASMs) among PWE. The objective of this study was to explore medication adherence and its relationship with self-esteem among individuals diagnosed with epilepsy in Isfahan, Iran.
METHODS: This descriptive-analytical study was conducted in the year 2021, encompassing a cohort of 250 PWE who were referred to designated medical facilities in Isfahan, Iran, and were selected by the consecutive sampling technique. A 3-part instrument including demographic components, the Rosenberg Self-Esteem Scale, and the Morissky Drug Adherence Questionnaire employed for data collection.
RESULTS: The mean and standard deviation of adherence to the medicinal regimen in the participants were 6.9 ± 2.02, and 46.4 % had a low level of adherence to the medication regimen (total score 0-6). At the same time, the mean and standard deviation of self-esteem in these patients was 5.11 ± 2.11. There was a statistically significant and direct correlation between adherence to the prescribed drug regimen and self-esteem (rs = 0.464, p = 0.00).
CONCLUSIONS: Based on the findings of the study that showed a statistically significant and positive correlation between self-esteem and adherence to the medication regimen, it is advisable to enhance and advocate for these factors in PWE.
METHODS: This descriptive-analytical study was conducted in the year 2021, encompassing a cohort of 250 PWE who were referred to designated medical facilities in Isfahan, Iran, and were selected by the consecutive sampling technique. A 3-part instrument including demographic components, the Rosenberg Self-Esteem Scale, and the Morissky Drug Adherence Questionnaire employed for data collection.
RESULTS: The mean and standard deviation of adherence to the medicinal regimen in the participants were 6.9 ± 2.02, and 46.4 % had a low level of adherence to the medication regimen (total score 0-6). At the same time, the mean and standard deviation of self-esteem in these patients was 5.11 ± 2.11. There was a statistically significant and direct correlation between adherence to the prescribed drug regimen and self-esteem (rs = 0.464, p = 0.00).
CONCLUSIONS: Based on the findings of the study that showed a statistically significant and positive correlation between self-esteem and adherence to the medication regimen, it is advisable to enhance and advocate for these factors in PWE.
摘要：
药物依从性对于实现预期的治疗结果和有效管理癫痫患者（PWE）的癫痫发作至关重要。必须认识到自尊是一种心理决定因素，可能会影响PWE中抗癫痫药物（ASM）的最佳依从性。本研究的目的是探讨伊斯法罕癫痫患者的服药依从性及其与自尊的关系。伊朗。
方法：这项描述性分析研究于2021年进行，包括250名PWE的队列，他们被转诊到伊斯法罕的指定医疗机构，伊朗,并通过连续采样技术选择。包括人口统计成分的三部分仪器，罗森博格自尊量表，和Morissky药物依从性问卷用于数据收集。
结果：参与者对药物治疗方案的依从性的平均值和标准差为6.9±2.02，46.4%的参与者对药物治疗方案的依从性较低（总分0-6）。同时,这些患者的自尊的平均值和标准差为5.11±2.11。对处方药物方案的依从性与自尊之间存在统计学上显着的直接相关性（rs=0.464，p=0.00）。
结论：根据研究结果显示，自尊与服药依从性之间具有统计学意义的正相关，建议在PWE中加强和倡导这些因素。
方法：这项描述性分析研究于2021年进行，包括250名PWE的队列，他们被转诊到伊斯法罕的指定医疗机构，伊朗,并通过连续采样技术选择。包括人口统计成分的三部分仪器，罗森博格自尊量表，和Morissky药物依从性问卷用于数据收集。
结果：参与者对药物治疗方案的依从性的平均值和标准差为6.9±2.02，46.4%的参与者对药物治疗方案的依从性较低（总分0-6）。同时,这些患者的自尊的平均值和标准差为5.11±2.11。对处方药物方案的依从性与自尊之间存在统计学上显着的直接相关性（rs=0.464，p=0.00）。
结论：根据研究结果显示，自尊与服药依从性之间具有统计学意义的正相关，建议在PWE中加强和倡导这些因素。
