PDF(Pubmed)
Abstract：
UNASSIGNED: Effective irrigation is crucial for successful endodontic treatment. Traditional irrigants like sodium hypochlorite (NaOCl) have been widely used, but there is a growing interest in exploring natural alternatives for their potential antimicrobial properties.
UNASSIGNED: The study aims to compare the antimicrobial efficacy of Neem, Bitter Gourd, and NaOCl, with and without ultrasonic activation in managing primary endodontic infections.
UNASSIGNED: Ninety patients were randomly assigned six groups (n = 15) Group 1: NaOCl, Group 2: NaOCl with passive ultrasonic irrigation (PUI), Group 3: Neem juice, Group 4: Neem juice with PUI, Group 5: Bitter gourd juice, and Group 6: Bitter gourd juice with PUI. Bacteriological samples were collected before (S1) and after (S2) shaping, plated on brain heart infusion agar, and colony counting was done after 24 h.
UNASSIGNED: Shapiro-Wilk test, one-way ANOVA, post hoc Tukey analysis, and paired t-test.
UNASSIGNED: All the groups demonstrated a significant reduction in bacterial count. Groups with PUI (2, 4, 6) demonstrated higher mean bacterial reduction than their counterparts without PUI (1, 3, 5).
UNASSIGNED: Neem and Bitter gourd juices, particularly when used with PUI, demonstrated antimicrobial efficacy comparable to NaOCl with PUI.
UNASSIGNED: The study aims to compare the antimicrobial efficacy of Neem, Bitter Gourd, and NaOCl, with and without ultrasonic activation in managing primary endodontic infections.
UNASSIGNED: Ninety patients were randomly assigned six groups (n = 15) Group 1: NaOCl, Group 2: NaOCl with passive ultrasonic irrigation (PUI), Group 3: Neem juice, Group 4: Neem juice with PUI, Group 5: Bitter gourd juice, and Group 6: Bitter gourd juice with PUI. Bacteriological samples were collected before (S1) and after (S2) shaping, plated on brain heart infusion agar, and colony counting was done after 24 h.
UNASSIGNED: Shapiro-Wilk test, one-way ANOVA, post hoc Tukey analysis, and paired t-test.
UNASSIGNED: All the groups demonstrated a significant reduction in bacterial count. Groups with PUI (2, 4, 6) demonstrated higher mean bacterial reduction than their counterparts without PUI (1, 3, 5).
UNASSIGNED: Neem and Bitter gourd juices, particularly when used with PUI, demonstrated antimicrobial efficacy comparable to NaOCl with PUI.
摘要：
■有效的灌溉对于成功的牙髓治疗至关重要。次氯酸钠(NaOCl)等传统灌溉剂已被广泛使用,但是人们对探索天然替代品的潜在抗菌特性越来越感兴趣。
■该研究旨在比较印尼红的抗菌功效，苦瓜,和NaOCl,在管理原发性牙髓感染中有无超声激活。
■90名患者被随机分配六组（n=15）第1组：NaOCl，第2组：NaOCl与被动超声冲洗（PUI），第三组:印尼糖汁,第4组：印尼糖汁与PUI，组5:苦瓜汁,和第6组：苦瓜汁与PUI。在成型前(S1)和成型后(S2)收集细菌样本，铺在脑心灌注琼脂上，24小时后进行菌落计数。
■Shapiro-Wilk检验，单向方差分析,事后Tukey分析，和配对t检验。
■所有组显示细菌计数显著减少。具有PUI的组(2,4,6)表现出比没有PUI的组(1,3,5)更高的平均细菌减少。
■印尼红和苦瓜汁，特别是与PUI一起使用时，表现出与使用PUI的NaOCl相当的抗微生物功效。
■该研究旨在比较印尼红的抗菌功效，苦瓜,和NaOCl,在管理原发性牙髓感染中有无超声激活。
■90名患者被随机分配六组（n=15）第1组：NaOCl，第2组：NaOCl与被动超声冲洗（PUI），第三组:印尼糖汁,第4组：印尼糖汁与PUI，组5:苦瓜汁,和第6组：苦瓜汁与PUI。在成型前(S1)和成型后(S2)收集细菌样本，铺在脑心灌注琼脂上，24小时后进行菌落计数。
■Shapiro-Wilk检验，单向方差分析,事后Tukey分析，和配对t检验。
■所有组显示细菌计数显著减少。具有PUI的组(2,4,6)表现出比没有PUI的组(1,3,5)更高的平均细菌减少。
■印尼红和苦瓜汁，特别是与PUI一起使用时，表现出与使用PUI的NaOCl相当的抗微生物功效。
