{Reference Type}: Journal Article {Title}: Antimicrobial efficacy of two commercially available herbal products with and without ultrasonic activation in primary endodontic infections: A randomized clinical trial. {Author}: Palwankar D;Garg A;Tandan M;Bhasin P;Sachdeva A;Palwankar P; {Journal}: J Conserv Dent Endod {Volume}: 27 {Issue}: 3 {Year}: 2024 Mar 暂无{DOI}: 10.4103/JCDE.JCDE_308_23 {Abstract}: UNASSIGNED: Effective irrigation is crucial for successful endodontic treatment. Traditional irrigants like sodium hypochlorite (NaOCl) have been widely used, but there is a growing interest in exploring natural alternatives for their potential antimicrobial properties.
UNASSIGNED: The study aims to compare the antimicrobial efficacy of Neem, Bitter Gourd, and NaOCl, with and without ultrasonic activation in managing primary endodontic infections.
UNASSIGNED: Ninety patients were randomly assigned six groups (n = 15) Group 1: NaOCl, Group 2: NaOCl with passive ultrasonic irrigation (PUI), Group 3: Neem juice, Group 4: Neem juice with PUI, Group 5: Bitter gourd juice, and Group 6: Bitter gourd juice with PUI. Bacteriological samples were collected before (S1) and after (S2) shaping, plated on brain heart infusion agar, and colony counting was done after 24 h.
UNASSIGNED: Shapiro-Wilk test, one-way ANOVA, post hoc Tukey analysis, and paired t-test.
UNASSIGNED: All the groups demonstrated a significant reduction in bacterial count. Groups with PUI (2, 4, 6) demonstrated higher mean bacterial reduction than their counterparts without PUI (1, 3, 5).
UNASSIGNED: Neem and Bitter gourd juices, particularly when used with PUI, demonstrated antimicrobial efficacy comparable to NaOCl with PUI.