关键词: Vogt-Koyanagi-Harada (VKH) syndrome adalimumab azathioprine exudative retinal detachment vitrectomy

来  源:   DOI:10.1177/11206721241247582

Abstract:
A 45-year-old male with Vogt-Koyanagi-Harada (VKH) syndrome presented with vision loss in his right eye after discontinuing treatment during the COVID-19 pandemic. He was found to have bullous retinal detachment (RD) in the right eye and was started on subcutaneous adalimumab with oral corticosteroid following three doses of pulse corticosteroid. But when RD did not resolve after 4 months of treatment and ultrasound B scan showed bullous RD with retino-retinal adhesion, he was planned for surgical intervention. During surgery, there was retino-retinal adhesions due to long-standing \"kissing exudative RD\", causing non-settling exudative RD. Following surgery, the vision improved to 2/60, with attached retina. The patient has been under follow-up with us for the last one year now and developed no recurrence of RD till now. This case emphasises the significance of retinoretinal adhesion in long-standing bullous RD that does not respond to conventional aggressive medical therapy.
摘要:
一名患有Vogt-Koyanagi-Harada(VKH)综合征的45岁男性在COVID-19大流行期间停止治疗后右眼视力下降。他被发现右眼有大疱性视网膜脱离(RD),并在三个剂量的脉冲皮质类固醇后开始接受阿达木单抗皮下口服皮质类固醇。但是当治疗4个月后RD没有消退,B超显示大疱性RD伴有视网膜-视网膜粘连时,他被计划进行手术干预。手术期间,由于长期的“亲吻渗出性RD”,视网膜视网膜粘连导致非沉降性渗出性RD。手术后,视力提高到2/60,附有视网膜。该患者在过去的一年中一直在接受我们的随访,并且到目前为止没有复发RD。该病例强调了视网膜视网膜粘连在长期大疱性RD中的重要性,该RD对常规的积极药物治疗没有反应。
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