关键词: Global PSQI Parkinson’s disease Sleep duration Sleep latency Sleep quality

Mesh : Humans Parkinson Disease / complications physiopathology Male Female Middle Aged Case-Control Studies Aged Sleep Quality Surveys and Questionnaires Sleep Wake Disorders / etiology Quality of Life

来  源:   DOI:10.1007/s11845-024-03689-3

Abstract:
BACKGROUND: Parkinson\'s disease (PD) is a common neurodegenerative disease that is linked to several motor and nonmotor symptoms, including sleep disturbances. Patient quality of life has been shown to be disproportionally impacted by disease.
OBJECTIVE: To investigate sleep quality among individuals with PD, and to assess the severity of sleep disturbances and their impact on daytime activities.
METHODS: A case‒control with 44 patients with Parkinson\'s disease and 80 apparently healthy control participants was recruited from several hospitals and clinics. Each participant provided a thorough medical history and underwent a physical examination, and a questionnaire comprising the standard PSQI was used to assess sleep quality. Independent samples t test and Spearman\'s correlation analysis were used with a p value equal to or less than 0.05 which was considered significant.
RESULTS: The mean global PSQI score was 11.55 ± 4.412 for PD patients and 5.73 ± 3.22 for the control group with significant p value, Sleep latency onset was 75.57 min for PD patients and 22.81 min for the control group with significant p value. There was no significant correlation between age and other sleep-related variables. A total of 86.4% of patients with Parkinson\'s disease suffered from varying degrees of daytime dysfunction compared to 61.25% of the controls.
CONCLUSIONS: Parkinson\'s disease patients had poorer sleep quality than the controls. Age and sex were not found to be expected as a factor for sleep quality in patients with Parkinson\'s disease. Daytime dysfunction rates are high in patients with Parkinson\'s disease.
摘要:
背景:帕金森病(PD)是一种常见的神经退行性疾病,与几种运动和非运动症状有关,包括睡眠障碍。患者的生活质量已被证明受到疾病的不成比例的影响。
目的:调查PD患者的睡眠质量,并评估睡眠障碍的严重程度及其对白天活动的影响。
方法:从几家医院和诊所招募了44名帕金森病患者和80名明显健康对照者的病例对照。每位参与者都提供了全面的病史并接受了身体检查,使用包含标准PSQI的问卷评估睡眠质量。使用独立样本t检验和Spearman相关性分析,p值等于或小于0.05,这被认为是显著的。
结果:PD患者的平均总体PSQI评分为11.55±4.412,对照组为5.73±3.22,具有显着的p值,PD患者的睡眠潜伏期为75.57min,对照组为22.81min,具有显着的p值。年龄与其他睡眠相关变量之间没有显着相关性。与对照组的61.25%相比,总共86.4%的帕金森病患者患有不同程度的日间功能障碍。
结论:帕金森病患者的睡眠质量低于对照组。年龄和性别并不是帕金森病患者睡眠质量的预期因素。帕金森病患者的日间功能障碍发生率较高。
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