{Reference Type}: Journal Article
{Title}: Does Parkinson's disease affect sleep quality?
{Author}: Hammadi HA;Hameed WA;Fakhri MA;Khazaal HM;Abood FK;Hameed EK;Al-Ameri LT;
{Journal}: Ir J Med Sci
{Volume}: 193
{Issue}: 4
{Year}: 2024 Aug 16
{Factor}: 2.089
{DOI}: 10.1007/s11845-024-03689-3
{Abstract}: <B>BACKGROUND: </B>Parkinson's disease (PD) is a common neurodegenerative disease that is linked to several motor and nonmotor symptoms, including sleep disturbances. Patient quality of life has been shown to be disproportionally impacted by disease.<BR><B>OBJECTIVE: </B>To investigate sleep quality among individuals with PD, and to assess the severity of sleep disturbances and their impact on daytime activities.<BR><B>METHODS: </B>A case‒control with 44 patients with Parkinson's disease and 80 apparently healthy control participants was recruited from several hospitals and clinics. Each participant provided a thorough medical history and underwent a physical examination, and a questionnaire comprising the standard PSQI was used to assess sleep quality. Independent samples t test and Spearman's correlation analysis were used with a p value equal to or less than 0.05 which was considered significant.<BR><B>RESULTS: </B>The mean global PSQI score was 11.55 ± 4.412 for PD patients and 5.73 ± 3.22 for the control group with significant p value, Sleep latency onset was 75.57 min for PD patients and 22.81 min for the control group with significant p value. There was no significant correlation between age and other sleep-related variables. A total of 86.4% of patients with Parkinson's disease suffered from varying degrees of daytime dysfunction compared to 61.25% of the controls.<BR><B>CONCLUSIONS: </B>Parkinson's disease patients had poorer sleep quality than the controls. Age and sex were not found to be expected as a factor for sleep quality in patients with Parkinson's disease. Daytime dysfunction rates are high in patients with Parkinson's disease.