Abstract：
Scorpions, a group of oldest animals with wide distribution in the world, have a long history of medicinal use. Scorpio, the dried body of Buthus martensii, is a rare animal medicine mainly used for the treatment of liver diseases, spasm, and convulsions in children in China. The venom has been considered as the active substance of scorpions. However, little is known about the small molecules in the venom of scorpions. According to the articles published in recent years, scorpions contain amino acids, fatty acids, steroids, and alkaloids, which endow scorpions with antimicrobial, anticoagulant, metabolism-regulating, and antitumor activities. This paper summarizes the small molecule chemical components and pharmacological activities of scorpions, with a view to providing valuable information for the discovery of new active molecules and the clinical use of scorpions.
摘要：
蝎子,一群世界上分布广泛的最古老的动物，具有悠久的药用历史。天蝎座,Buthusmartensii的干燥身体，是一种珍稀动物药，主要用于治疗肝脏疾病，痉挛,中国儿童的抽搐。毒液被认为是蝎子的活性物质。然而,对蝎子毒液中的小分子知之甚少。根据近年来发表的文章，蝎子含有氨基酸,脂肪酸，类固醇,和生物碱，赋予蝎子抗菌药物，抗凝剂,新陈代谢调节，和抗肿瘤活性。本文综述了蝎子的小分子化学成分和药理活性,以期为蝎子新活性分子的发现和临床应用提供有价值的信息。
