Abstract：
This study elucidated the effects of a three-dimensional k-space trajectory incorporating the partial Fourier (PF) technique on a time-intensity curve (TIC) in a dynamic contrast-enhanced magnetic resonance imaging of a typical malignant breast tumor using a digital phantom. Images were obtained from the Cancer Imaging Archive Open Data for Breast Cancer, and 1-min scans with high temporal resolution were analyzed. The order of the k-space trajectory was set as Linear (sequential), Low-High (centric), PF (62.5%; Z-, Y-, and both directions), and Low-High Radial. k0 (center of the k-space) timing and TIC shape were affected by the chosen k-space trajectory and implementation of the PF technique. A small TIC gradient was obtained using a Low-High Radial order. If the k-space filling method (particularly the radial method) produces a gentle TIC gradient, misinterpretation could arise during the assessment of tumor malignancy status.
摘要：
这项研究阐明了在使用数字体模对典型恶性乳腺肿瘤进行动态对比增强磁共振成像时，结合部分傅立叶（PF）技术的三维k空间轨迹对时间强度曲线（TIC）的影响。图像来自乳腺癌的癌症成像档案开放数据，分析了具有高时间分辨率的1分钟扫描。k空间轨迹的顺序设置为线性（顺序），低-高（中心），PF（62.5%；Z-，Y-,和两个方向)，和低高径向。k0(k空间的中心)定时和TIC形状受到所选择的k空间轨迹和PF技术的实施的影响。使用低-高径向阶次获得小的TIC梯度。如果k空间填充方法（特别是径向方法）产生平缓的TIC梯度，在评估肿瘤恶性程度时可能会出现误解.
