PDF(Pubmed)
Abstract：
Trace elements are essential for maintaining the body\'s homeostasis, and their special role has been demonstrated in skin physiology. Among the most important trace elements are zinc, copper, and iron. A deficiency or excess of trace elements can be associated with an increased risk of skin diseases, so increasing their supplementation or limiting intake can be helpful in dermatological treatment. In addition, determinations of their levels in various types of biological material can be useful as additional tests in dermatological treatment. This paper describes the role of these elements in skin physiology and summarizes data on zinc, copper, and iron in the course of selected, following skin diseases: psoriasis, pemphigus vulgaris, atopic dermatitis, acne vulgaris and seborrheic dermatitis. In addition, this work identifies the potential of trace elements as auxiliary tests in dermatology. According to preliminary studies, abnormal levels of zinc, copper, and iron are observed in many skin diseases and their determinations in serum or hair can be used as auxiliary and prognostic tests in the course of various dermatoses. However, since data for some conditions are conflicting, clearly defining the potential of trace elements as auxiliary tests or elements requiring restriction/supplement requires further research.
摘要：
微量元素是维持身体稳态所必需的,它们的特殊作用已经在皮肤生理学中得到证实。其中最重要的微量元素是锌，铜，和铁。微量元素的缺乏或过量可能与皮肤病的风险增加有关，因此，增加他们的补充或限制摄入量可能有助于皮肤病治疗。此外,它们在各种类型的生物材料中的水平的测定可以用作皮肤病治疗中的附加测试。本文介绍了这些元素在皮肤生理中的作用，并总结了有关锌的数据，铜，和铁在选定的过程中，以下皮肤病：牛皮癣，寻常型天疱疮,特应性皮炎,寻常痤疮和脂溢性皮炎。此外,这项工作确定了微量元素作为皮肤病学辅助测试的潜力。根据初步研究,锌含量异常,铜，在许多皮肤病中观察到铁和铁，它们在血清或头发中的测定可用作各种皮肤病过程中的辅助和预后测试。然而,由于某些条件的数据是冲突的，明确定义微量元素作为辅助测试或需要限制/补充的元素的潜力需要进一步研究。
