Abstract:
Thoracolumbar intervertebral disc disease (IVDD) is the most common cause of spinal injury in dogs. MRI has been considered the gold standard for neurologic diagnosis, but studies focusing on the thoracolumbar spinal canal and spinal cord using MRI in small-breed dogs are limited. Therefore, this study aimed to establish an MRI reference range for the spinal cord and canal measurements (height, width, cord-to-canal ratio of height, width, cross-sectional area (CSA)) of each intervertebral disc level from T11 to L5 (total of seven levels) on transverse T2-weighted images in normal small-breed dogs. We hypothesized that the spinal cord and spinal canal measurements might vary according to the body weight and age. The width and height of the spinal cord and canal increased as the body weight increased at all levels (p < 0.05). The cord-to-canal ratio of the width showed a negative correlation to the body weight at all levels. The cord-to-canal ratio of the height did not show any correlation to the body weight at all levels. All measurements (height, width, cord-to-canal ratio of height, width, CSA) did not show any statistical correlation between the groups subdivided by age. These measurements could serve as a morphometric baseline for thoracolumbar spinal diseases and clinical research in small-breed dogs.
摘要:
胸腰椎椎间盘疾病(IVDD)是犬脊髓损伤的最常见原因。MRI被认为是神经系统诊断的金标准,但是在小型犬中使用MRI对胸腰椎椎管和脊髓进行的研究有限.因此,这项研究旨在建立脊髓和椎管测量的MRI参考范围(高度,宽度,绳索与运河的高度比,宽度,在正常小型犬的横向T2加权图像上,从T11到L5的每个椎间盘水平(总共七个水平)的横截面积(CSA))。我们假设脊髓和椎管的测量值可能会根据体重和年龄而变化。脊髓和椎管的宽度和高度随着各级体重的增加而增加(p<0.05)。在所有水平上,宽度的索与管之比与体重呈负相关。在所有水平上,身高的索与管之比与体重均无任何相关性。所有测量值(高度,宽度,绳索与运河的高度比,宽度,CSA)未显示按年龄细分的组之间的任何统计相关性。这些测量结果可作为小型犬胸腰椎脊柱疾病和临床研究的形态基线。