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Abstract：
This comparative cross-sectional study, conducted at Shanghai Pulmonary Hospital, aimed to evaluate the efficacy of tailored wound-centric interventions (TWCI) versus traditional pulmonary rehabilitation (TPR) in enhancing wound healing in patients with chronic obstructive pulmonary disease (COPD). Enrolling 340 patients with confirmed COPD, the study randomly assigned participants to either the TWCI or TPR group for a 12-week programme. The primary outcome measured was the rate of wound healing, with secondary outcomes including changes in pulmonary function tests (PFTs) and quality of life (QoL) scores. The TWCI group received a customized programme integrating standard pulmonary rehabilitation with specific wound care strategies, such as enhanced oxygen therapy, nutritional supplementation, and infection control measures. In contrast, the TPR group underwent a conventional pulmonary rehabilitation programme without targeted wound care interventions. Wound healing rates, PFTs, and QoL scores were assessed at the end of the intervention and 3 months post-intervention. The TWCI group demonstrated a statistically significant improvement in wound healing rates compared with the TPR group. The TWCI group had a 15% higher rate of reduction in wound size, a 10% rise in complete healing rates, and a 20% drop in infection rates (p < 0.05). Specifically, TWCI group exhibited higher rates of wound size reduction, complete healing, and decreased infection rates. Additionally, long-term pulmonary function and overall quality of life improvements were more pronounced in the tailored group, underscoring the benefits of a personalized approach to managing COPD and wound care. The study concluded that integrating wound-specific care strategies with pulmonary rehabilitation significantly enhances health outcomes in COPD patients with wounds. These findings supported the adoption of customized, multidisciplinary care plans, suggesting that tailored interventions can offer a comprehensive solution to the complex needs of COPD patients, potentially redefining best practices in chronic disease management.
摘要：
这项比较横断面研究，在上海肺科医院进行，旨在评估量身定制的以伤口为中心的干预措施（TWCI）与传统肺康复（TPR）在促进慢性阻塞性肺疾病（COPD）患者伤口愈合方面的疗效。纳入340例确诊COPD患者，本研究将参与者随机分配至TWCI或TPR组,为期12周.测量的主要结果是伤口愈合率，次要结局包括肺功能测试（PFTs）和生活质量（QoL）评分的变化。TWCI小组接受了一项定制计划，将标准的肺康复与特定的伤口护理策略相结合，比如强化氧疗,营养补充,和感染控制措施。相比之下,TPR组接受了常规的肺康复计划,没有针对性的伤口护理干预.伤口愈合率,PFTs,和QoL评分在干预结束时和干预后3个月进行评估.与TPR组相比，TWCI组的伤口愈合率有统计学上的显着改善。TWCI组有15%的伤口大小减少率，完全愈合率提高10%,感染率下降20%(p<0.05)。具体来说,TWCI组伤口大小缩小率较高，完全愈合，降低感染率。此外,长期肺功能和整体生活质量改善在定制组中更为明显，强调个性化方法管理COPD和伤口护理的益处。该研究得出结论，将伤口特异性护理策略与肺康复相结合可显着提高COPD伤口患者的健康结局。这些发现支持采用定制的，多学科护理计划，这表明量身定制的干预措施可以为COPD患者的复杂需求提供全面的解决方案，可能重新定义慢性病管理的最佳实践。
