Mesh : Female Child Humans Child, Preschool Pyridostigmine Bromide / therapeutic use Myasthenia Gravis / complications diagnosis Blepharoptosis / diagnosis etiology Ophthalmoplegia / diagnosis etiology Receptors, Cholinergic Autoantibodies

来  源:   DOI:10.5693/djo.02.2023.09.002   PDF(Pubmed)

Abstract:
We report 2 cases of pediatric ocular myasthenia gravis. The first case was a 7-year-old girl who presented with bilateral ophthalmoplegia and ptosis that correlated with the onset of upper respiratory symptoms. Neuroimaging and acetylcholine receptor antibody testing were unremarkable. The ice pack test was positive. Symptoms greatly improved with pyridostigmine, with full resolution of ophthalmoplegia achieved by 8-month follow-up. The second case was a 4-year-old girl who presented emergently with ptosis and bilateral ophthalmoplegia. Acetylcholine receptor antibodies testing was positive. The patient was started on pyridostigmine and intravenous immunoglobulin and is scheduled to follow-up with pediatric ophthalmology in the outpatient setting.
摘要:
我们报告2例小儿眼肌无力。第一例是一名7岁女孩,表现为双侧眼肌麻痹和上清液,与上呼吸道症状的发作有关。神经影像学和乙酰胆碱受体抗体检测无明显变化。冰袋测试是阳性的。吡啶斯的明的症状大大改善,通过8个月的随访,实现了眼肌麻痹的完全解决。第二例是一名4岁女孩,她紧急出现上睑下垂和双侧眼肌麻痹。乙酰胆碱受体抗体检测呈阳性。患者开始接受吡啶斯的明和静脉注射免疫球蛋白,并计划在门诊进行儿科眼科随访。
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