Abstract:
Spermatocytic tumor is a very rare germ cell testicular neoplasm that accounts for less than 1% of testicular cancers. It generally affects older men with a mean age of 53.6 years (range 19-92 years). Spermatocytic tumor is classified within the group of germ cell tumors not related to germ cell neoplasia in situ. It presents clinicopathological characteristics different from classic seminoma and is not considered a variant of the latter. Due to a morphologic overlap with classical seminoma, it was called \"sperm cell seminoma\" in the past. The anaplastic variant of spermatocytic tumor is exceptional, few cases have been described in the literature, it presents an earlier onset compared to spermatocytic tumor and a benign behavior despite showing histological patterns similar to classic seminoma. We present the second case of bilateral synchronous anaplastic spermatocytic tumor, in a young patient treated with orchiectomy and chemotherapy.
摘要:
精母细胞瘤是一种非常罕见的生殖细胞睾丸肿瘤,占睾丸癌的不到1%。它通常影响平均年龄为53.6岁(范围19-92岁)的老年男性。精母细胞肿瘤被分类在与原位生殖细胞瘤不相关的生殖细胞肿瘤组中。它具有与经典精原细胞瘤不同的临床病理特征,不被认为是后者的变体。由于与经典精原细胞瘤的形态学重叠,它在过去被称为“精子细胞精原细胞瘤”。精原细胞肿瘤的间变性变种是特殊的,文献中很少描述案例,尽管显示出与经典精原细胞瘤相似的组织学模式,但与精原细胞瘤相比,它表现出更早的发病和良性行为。我们介绍了第二例双侧同步间变性精原细胞肿瘤,一名接受睾丸切除术和化疗的年轻患者。