METHODS: Before the actual experiment, the individual olfactory threshold for the rose-like odorant phenylethyl alcohol (PEA) was assessed separately for the left and right nostril using the \"Sniffin\' Sticks\" test, and ratings for odor intensity and pleasantness were collected. After applying a nasal clip continuously delivering PEA odor to one nostril for 10 min and 2 h, respectively, threshold, intensity, and pleasantness were reassessed immediately after clip removal.
RESULTS: In the group of 80 participants (younger adults-mean age 27.7 ± 4.5 years; older adults-mean age 61.5 ± 4.7 years), olfactory thresholds were already significantly elevated after just 10 min, and this habituation was even more pronounced after 2 h. This effect could be observed bilaterally even though significantly more distinct on the exposed side. Older participants generally exhibited a more pronounced habituation on the exposed side after 2 h compared to the younger participants.
CONCLUSIONS: The results indicate that older people experience more notable habituation after extended exposure to odors. This is most likely due to the compromised olfactory function in age. Although older and younger subjects scored in the normosmic range when tested with standardized olfactory tests, the stress on the system after exposure to an odor clearly revealed the lower functionality of the aging sense of smell.
METHODS: 3 Laryngoscope, 134:3765-3768, 2024.
方法:在实际实验之前,使用“Sniffin\'Sticks\”测试分别评估左鼻孔和右鼻孔的玫瑰样气味苯乙醇(PEA)的个体嗅觉阈值,并收集气味强度和愉悦度的评级。应用鼻夹连续向一个鼻孔传递PEA气味10分钟和2小时后,分别,阈值,强度,移除夹子后,立即重新评估愉悦感。
结果:在80名参与者中(年轻人-平均年龄27.7±4.5岁;老年人-平均年龄61.5±4.7岁),仅仅10分钟后,嗅觉阈值就已经显著升高,2小时后,这种习惯更加明显。即使在暴露侧明显更明显,也可以在双边观察到这种影响。与年轻参与者相比,年龄较大的参与者通常在2小时后在暴露侧表现出更明显的习惯。
结论:结果表明,老年人在长期接触气味后,会有更明显的习惯。这很可能是由于年龄的嗅觉功能受损。尽管年龄较大和较年轻的受试者在进行标准嗅觉测试时得分在正常范围内,暴露于气味后对系统的压力清楚地揭示了老化嗅觉的较低功能。
方法:3喉镜,2024.