关键词: Aspergillus versicolor spondylitis antifungal treatment immunocompetent patient macrogene sequencing spine voriconazole

Mesh : Humans Antifungal Agents / therapeutic use Aspergillosis / diagnosis drug therapy microbiology Aspergillus Spondylarthritis Spondylitis / diagnostic imaging drug therapy

来  源:   DOI:10.1177/03000605241234574   PDF(Pubmed)

Abstract:
Blood-disseminated Aspergillus spondylitis in immunocompetent individuals is rare. The clinical, imaging, and pathological manifestations of this condition are not specific. Therefore, this disease is prone to misdiagnosis and a missed diagnosis. Systemic antifungal therapy is the main treatment for Aspergillus spondylitis. We report a case of blood-disseminated Aspergillus versicolor spondylitis in a patient with normal immune function. The first antifungal treatment lasted for 4 months, but Aspergillus spondylitis recurred a few months later. A second antifungal treatment course was initiated for at least 1 year, and follow-up has been ongoing. Currently, there has been no recurrence.
摘要:
在免疫功能正常的个体中,血液播散的曲霉脊柱炎很少见。临床,成像,这种情况的病理表现并不具体。因此,这种疾病容易误诊和漏诊。全身抗真菌治疗是曲霉菌脊柱炎的主要治疗方法。我们报告了一例免疫功能正常的患者的血液播散性杂色曲霉脊柱炎。第一次抗真菌治疗持续了4个月,但是曲霉性脊柱炎几个月后又复发了。开始第二个抗真菌治疗疗程至少1年,后续行动一直在进行。目前,没有复发。
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