白藜芦醇通过调节 AMPK 途径激活自噬并保护人皮肤成纤维细胞和雄性小鼠皮肤免受 UVA 诱导的光老化。
关键词: AMPK Autophagy Photoaging ROS Resveratrol UVA
Mesh : Resveratrol / pharmacology Skin Aging / drug effects radiation effects Fibroblasts / drug effects radiation effects metabolism Autophagy / drug effects radiation effects Animals Ultraviolet Rays / adverse effects Humans Male AMP-Activated Protein Kinases / metabolism Mice Skin / drug effects radiation effects pathology metabolism Stilbenes / pharmacology Signal Transduction / drug effects Reactive Oxygen Species / metabolism Antioxidants / pharmacology Apoptosis / drug effects radiation effects
来 源:
DOI:10.1007/s10522-024-10099-6
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