Abstract：
BACKGROUND: Between 10% and 15% of people with hypothyroidism experience persistent symptoms, despite achieving biochemical euthyroidism. The underlying causes are unclear. Type D personality (a vulnerability factor for general psychological distress) is associated with poor health status and symptom burden but has not been studied in people with hypothyroidism.
OBJECTIVE: To investigate type D personality in hypothyroidism and explore associations with other characteristics and patient-reported outcomes.
METHODS: Multinational, cross-sectional survey.
METHODS: Online.
METHODS: Individuals with self-reported, treated hypothyroidism.
METHODS: Questionnaire.
METHODS: Type D personality and associations with baseline characteristics, control of the symptoms of hypothyroidism by medication, satisfaction with care and treatment of hypothyroidism, impact of hypothyroidism on everyday living.
RESULTS: A total of 3915 responses were received, 3523 of which were valid. The prevalence of type D personality was 54.2%. Statistically significant associations were found between type D personality and several respondent characteristics (age, marital status, ethnicity, household income, comorbidities, type of treatment for hypothyroidism, most recent TSH level), anxiety, depression, somatization, poor control of the symptoms of hypothyroidism by medication, dissatisfaction with care and treatment of hypothyroidism, and a negative impact of hypothyroidism on everyday living).
CONCLUSIONS: Our study found a high prevalence of type D personality among people with hypothyroidism who responded to the survey. Type D personality may be an important determinant of dissatisfaction with treatment and care among people with hypothyroidism. Our findings require independent confirmation. Close collaboration between the disciplines of thyroidology and psychology is likely to be key in progressing our understanding in this area.
OBJECTIVE: To investigate type D personality in hypothyroidism and explore associations with other characteristics and patient-reported outcomes.
METHODS: Multinational, cross-sectional survey.
METHODS: Online.
METHODS: Individuals with self-reported, treated hypothyroidism.
METHODS: Questionnaire.
METHODS: Type D personality and associations with baseline characteristics, control of the symptoms of hypothyroidism by medication, satisfaction with care and treatment of hypothyroidism, impact of hypothyroidism on everyday living.
RESULTS: A total of 3915 responses were received, 3523 of which were valid. The prevalence of type D personality was 54.2%. Statistically significant associations were found between type D personality and several respondent characteristics (age, marital status, ethnicity, household income, comorbidities, type of treatment for hypothyroidism, most recent TSH level), anxiety, depression, somatization, poor control of the symptoms of hypothyroidism by medication, dissatisfaction with care and treatment of hypothyroidism, and a negative impact of hypothyroidism on everyday living).
CONCLUSIONS: Our study found a high prevalence of type D personality among people with hypothyroidism who responded to the survey. Type D personality may be an important determinant of dissatisfaction with treatment and care among people with hypothyroidism. Our findings require independent confirmation. Close collaboration between the disciplines of thyroidology and psychology is likely to be key in progressing our understanding in this area.
摘要：
背景：10％至15％的甲状腺功能减退症患者会出现持续的症状，尽管实现了生化甲状腺功能正常。根本原因尚不清楚。D型人格（一般心理困扰的脆弱性因素）与不良的健康状况和症状负担有关，但尚未在甲状腺功能减退症患者中进行研究。
目的：调查甲状腺功能减退症患者的D型人格，并探讨与其他特征和患者报告结局的关系。
方法：多国，横断面调查。
方法：在线。
方法：自我报告的个人，治疗甲状腺功能减退。
方法：问卷调查。
方法：D型人格和与基线特征的关联，通过药物控制甲状腺功能减退的症状，对甲状腺功能减退症的护理和治疗满意度，甲状腺功能减退症对日常生活的影响。
结果：共收到3915份回复，其中3523是有效的。D型人格患病率为54.2%。在D型人格和几个受访者特征(年龄，婚姻状况,种族,家庭收入,合并症,甲状腺功能减退症的治疗类型，最近的TSH水平)，焦虑,抑郁症,躯体化，通过药物对甲状腺功能减退症的症状控制不佳，对甲状腺功能减退症的护理和治疗不满，以及甲状腺功能减退症对日常生活的负面影响）。
结论：我们的研究发现，在接受调查的甲状腺功能减退症患者中，D型人格的患病率很高。D型人格可能是甲状腺功能减退症患者对治疗和护理不满的重要决定因素。我们的发现需要独立确认。甲状腺和心理学学科之间的密切合作可能是提高我们在这一领域理解的关键。
目的：调查甲状腺功能减退症患者的D型人格，并探讨与其他特征和患者报告结局的关系。
方法：多国，横断面调查。
方法：在线。
方法：自我报告的个人，治疗甲状腺功能减退。
方法：问卷调查。
方法：D型人格和与基线特征的关联，通过药物控制甲状腺功能减退的症状，对甲状腺功能减退症的护理和治疗满意度，甲状腺功能减退症对日常生活的影响。
结果：共收到3915份回复，其中3523是有效的。D型人格患病率为54.2%。在D型人格和几个受访者特征(年龄，婚姻状况,种族,家庭收入,合并症,甲状腺功能减退症的治疗类型，最近的TSH水平)，焦虑,抑郁症,躯体化，通过药物对甲状腺功能减退症的症状控制不佳，对甲状腺功能减退症的护理和治疗不满，以及甲状腺功能减退症对日常生活的负面影响）。
结论：我们的研究发现，在接受调查的甲状腺功能减退症患者中，D型人格的患病率很高。D型人格可能是甲状腺功能减退症患者对治疗和护理不满的重要决定因素。我们的发现需要独立确认。甲状腺和心理学学科之间的密切合作可能是提高我们在这一领域理解的关键。
