Abstract：
BACKGROUND: The current study reported a case with a history of neuroradiculitis. Within 2 months of the COVID-19 vaccine, critical Guillain-Barre Syndrome (GBS) appeared after acute diarrhea, progressive myasthenia, and sudden respiratory and cardiac symptoms.
METHODS: The syndrome was addressed with measures, such as endotracheal intubation and cardiopulmonary resuscitation vasoactive drugs. Next, we conducted six cycles of human immunoglobulin treatment (dose of 400 mg/kg·d intravenously for 5 days consecutively) and three times plasma exchange (PE, 30 ml/kg), followed by methylprednisolone sodium succinate. Rehabilitation training was carried out continuously.
RESULTS: The consciousness of the patient returned to normal, wherein he carried out normal communication. The muscle strength recovered gradually but still could not stand independently. Presently, he is recovering at home.
CONCLUSIONS: For patients with previous radiculitis, COVID-19 vaccination may increase the susceptibility to GBS. Thus, it is recommended to extend the vaccination interval for these patients and ensure that any potential increased risk is continually assessed.
METHODS: The syndrome was addressed with measures, such as endotracheal intubation and cardiopulmonary resuscitation vasoactive drugs. Next, we conducted six cycles of human immunoglobulin treatment (dose of 400 mg/kg·d intravenously for 5 days consecutively) and three times plasma exchange (PE, 30 ml/kg), followed by methylprednisolone sodium succinate. Rehabilitation training was carried out continuously.
RESULTS: The consciousness of the patient returned to normal, wherein he carried out normal communication. The muscle strength recovered gradually but still could not stand independently. Presently, he is recovering at home.
CONCLUSIONS: For patients with previous radiculitis, COVID-19 vaccination may increase the susceptibility to GBS. Thus, it is recommended to extend the vaccination interval for these patients and ensure that any potential increased risk is continually assessed.
摘要：
背景：目前的研究报告了一例有神经泌尿道炎病史的病例。在COVID-19疫苗接种的2个月内，急性腹泻后出现严重的格林-巴利综合征（GBS），进行性肌无力,以及突然的呼吸和心脏症状.
方法：通过措施解决了综合征，如气管插管和心肺复苏血管活性药物。接下来,我们进行了6个周期的人免疫球蛋白治疗（剂量为400mg/kg·d，连续5天）和3次血浆置换（PE，30ml/kg)，其次是甲基强的松龙琥珀酸钠。康复训练持续进行。
结果：患者意识恢复正常，他进行了正常的交流。肌肉力量逐渐恢复，但仍不能独立站立。目前,他正在家里康复。
结论：对于先前患有神经根炎的患者，COVID-19疫苗接种可能会增加对GBS的易感性。因此，建议延长这些患者的疫苗接种间隔,并确保持续评估任何可能增加的风险.
方法：通过措施解决了综合征，如气管插管和心肺复苏血管活性药物。接下来,我们进行了6个周期的人免疫球蛋白治疗（剂量为400mg/kg·d，连续5天）和3次血浆置换（PE，30ml/kg)，其次是甲基强的松龙琥珀酸钠。康复训练持续进行。
结果：患者意识恢复正常，他进行了正常的交流。肌肉力量逐渐恢复，但仍不能独立站立。目前,他正在家里康复。
结论：对于先前患有神经根炎的患者，COVID-19疫苗接种可能会增加对GBS的易感性。因此，建议延长这些患者的疫苗接种间隔,并确保持续评估任何可能增加的风险.
