Abstract：
BACKGROUND: Data from patients with post-ablative dural defects reconstructed using a free temporalis muscle fascia graft (FTFG) after resection of anterior or central skull base tumors were retrospectively analyzed.
METHODS: The primary predictor and outcome variables were the reconstructive methods for dural repair and postoperative cerebrospinal fluid (CSF) leakage rate, respectively.
RESULTS: Eighty patients were included, and 94 postoperative dural reconstructions were performed using FTFG. The postoperative CSF leakage rate was 3.19%. The postoperative CSF leakage rates did not significantly differ between open and endonasal endoscopic surgeries (1.92% vs. 4.88%; p > 0.05). In cases completed using the endonasal endoscopic approach, the postoperative CSF leakage rate was significantly associated with the intraoperative CSF leak flow (p < 0.05).
CONCLUSIONS: Post-ablative dural defect reconstruction using FTFG resulted in low postoperative CSF leakage and complication rates comparable to those of free fascia lata graft from available literature.
METHODS: The primary predictor and outcome variables were the reconstructive methods for dural repair and postoperative cerebrospinal fluid (CSF) leakage rate, respectively.
RESULTS: Eighty patients were included, and 94 postoperative dural reconstructions were performed using FTFG. The postoperative CSF leakage rate was 3.19%. The postoperative CSF leakage rates did not significantly differ between open and endonasal endoscopic surgeries (1.92% vs. 4.88%; p > 0.05). In cases completed using the endonasal endoscopic approach, the postoperative CSF leakage rate was significantly associated with the intraoperative CSF leak flow (p < 0.05).
CONCLUSIONS: Post-ablative dural defect reconstruction using FTFG resulted in low postoperative CSF leakage and complication rates comparable to those of free fascia lata graft from available literature.
摘要：
背景：回顾性分析前颅底或中央颅底肿瘤切除后使用颞肌筋膜游离移植物（FTFG）重建的消融后硬膜缺损患者的数据。
方法：主要预测因素和结果变量是硬膜修复的重建方法和术后脑脊液（CSF）漏发生率，分别。
结果：纳入80例患者，使用FTFG进行了94例术后硬膜重建。术后脑脊液漏出率为3.19%。开放手术和经鼻内镜手术的术后脑脊液漏发生率无显著差异(1.92%vs.4.88%；p>0.05）。在使用经鼻内镜入路完成的病例中，术后脑脊液漏发生率与术中脑脊液漏流量显著相关(p<0.05).
结论：使用FTFG的消融后硬脑膜缺损重建术后脑脊液漏和并发症发生率与现有文献中的游离筋膜移植物相当。
方法：主要预测因素和结果变量是硬膜修复的重建方法和术后脑脊液（CSF）漏发生率，分别。
结果：纳入80例患者，使用FTFG进行了94例术后硬膜重建。术后脑脊液漏出率为3.19%。开放手术和经鼻内镜手术的术后脑脊液漏发生率无显著差异(1.92%vs.4.88%；p>0.05）。在使用经鼻内镜入路完成的病例中，术后脑脊液漏发生率与术中脑脊液漏流量显著相关(p<0.05).
结论：使用FTFG的消融后硬脑膜缺损重建术后脑脊液漏和并发症发生率与现有文献中的游离筋膜移植物相当。
